Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain

Despite the measures adopted, levels of organochlorine compounds (OCs) are still being detected in the human body. This study aimed to explore factors related to changes in the concentrations of polychlorinated biphenyls (PCBs) and pesticide OCs in blood samples obtained from a general population co...

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Autores: Zubero Oleagoitia, Miren Begoña, Aurrekoetxea Agirre, Juan José, Murcia, Mario, Ibarluzea Maurolagoitia, Jesús María, Goñi, Fernando, Jiménez, Cristina, Ballester, Ferrán
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/65099
Acceso en línea:http://hdl.handle.net/10810/65099
Access Level:acceso abierto
Palabra clave:organochlorine pesticides
polychlorinated biphenyls serum
general population
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spelling Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, SpainZubero Oleagoitia, Miren BegoñaAurrekoetxea Agirre, Juan JoséMurcia, MarioIbarluzea Maurolagoitia, Jesús MaríaGoñi, FernandoJiménez, CristinaBallester, Ferránorganochlorine pesticidespolychlorinated biphenyls serumgeneral populationDespite the measures adopted, levels of organochlorine compounds (OCs) are still being detected in the human body. This study aimed to explore factors related to changes in the concentrations of polychlorinated biphenyls (PCBs) and pesticide OCs in blood samples obtained from a general population cohort. Two cross-sectional samples were taken from 162 adults (2–75 years of age), with a gap of 2 years, from four areas in Biscay (Spain). More than 75 % had quantifiable levels of hexachlorobenzene (HCB), beta-hexachlorocyclohexane (b-HCH), dichlorodiphenyldichloroethylene, and PCBs 138 153 and 180. During this time, significant changes were observed: PCB 180 and HCB levels increased, and PCB 138 and b-HCH levels decreased. Regarding age, this study shows a decrease suggesting a cohort effect. The period was not related to the decrease of levels in all age intervals, but a statistically significant increase of PCBs in older people was found. High body mass index was associated with lower PCB 180 levels and greater HCH levels. Inversely, greater levels of HCB and b-HCH were in those who had lost weight before the study. Levels of HCB and b-HCH were also greater in women who had had children, although they were lower in those who breastfed. Levels of these same OCs were greater in fish consumers, whereas those of PCBs 138 and 153 were greater in those who consumed local produce; all of these trends were close to significance. Efforts should continue to decrease exposure to these pollutants and to assess their influence on general population.Springer202420242015info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/65099reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoIngléshttps://link.springer.com/article/10.1007/s00244-014-0107-6info:eu-repo/semantics/openAccess© 2015, Springer Science+Business Media New Yorkoai:addi.ehu.eus:10810/650992026-06-18T09:23:17Z
dc.title.none.fl_str_mv Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
title Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
spellingShingle Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
Zubero Oleagoitia, Miren Begoña
organochlorine pesticides
polychlorinated biphenyls serum
general population
title_short Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
title_full Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
title_fullStr Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
title_full_unstemmed Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
title_sort Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain
dc.creator.none.fl_str_mv Zubero Oleagoitia, Miren Begoña
Aurrekoetxea Agirre, Juan José
Murcia, Mario
Ibarluzea Maurolagoitia, Jesús María
Goñi, Fernando
Jiménez, Cristina
Ballester, Ferrán
author Zubero Oleagoitia, Miren Begoña
author_facet Zubero Oleagoitia, Miren Begoña
Aurrekoetxea Agirre, Juan José
Murcia, Mario
Ibarluzea Maurolagoitia, Jesús María
Goñi, Fernando
Jiménez, Cristina
Ballester, Ferrán
author_role author
author2 Aurrekoetxea Agirre, Juan José
Murcia, Mario
Ibarluzea Maurolagoitia, Jesús María
Goñi, Fernando
Jiménez, Cristina
Ballester, Ferrán
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv organochlorine pesticides
polychlorinated biphenyls serum
general population
topic organochlorine pesticides
polychlorinated biphenyls serum
general population
description Despite the measures adopted, levels of organochlorine compounds (OCs) are still being detected in the human body. This study aimed to explore factors related to changes in the concentrations of polychlorinated biphenyls (PCBs) and pesticide OCs in blood samples obtained from a general population cohort. Two cross-sectional samples were taken from 162 adults (2–75 years of age), with a gap of 2 years, from four areas in Biscay (Spain). More than 75 % had quantifiable levels of hexachlorobenzene (HCB), beta-hexachlorocyclohexane (b-HCH), dichlorodiphenyldichloroethylene, and PCBs 138 153 and 180. During this time, significant changes were observed: PCB 180 and HCB levels increased, and PCB 138 and b-HCH levels decreased. Regarding age, this study shows a decrease suggesting a cohort effect. The period was not related to the decrease of levels in all age intervals, but a statistically significant increase of PCBs in older people was found. High body mass index was associated with lower PCB 180 levels and greater HCH levels. Inversely, greater levels of HCB and b-HCH were in those who had lost weight before the study. Levels of HCB and b-HCH were also greater in women who had had children, although they were lower in those who breastfed. Levels of these same OCs were greater in fish consumers, whereas those of PCBs 138 and 153 were greater in those who consumed local produce; all of these trends were close to significance. Efforts should continue to decrease exposure to these pollutants and to assess their influence on general population.
publishDate 2015
dc.date.none.fl_str_mv 2015
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/65099
url http://hdl.handle.net/10810/65099
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://link.springer.com/article/10.1007/s00244-014-0107-6
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
© 2015, Springer Science+Business Media New York
eu_rights_str_mv openAccess
rights_invalid_str_mv © 2015, Springer Science+Business Media New York
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
repository.name.fl_str_mv
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