MEDLINE-based assessment of animal studies on Chinese herbal medicine.

Ethno-pharmacological relevance: The scientific proof and clinical validation of Chinese herbal medicine (CHM) require a rigorous approach that includes chemical standardization, biological assays, animal studies and clinical trials. Aim of the study: To assess the experimental design of animal stud...

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Detalles Bibliográficos
Autores: Tejedor García, Noelia, Garcia Bermejo, Laura, Fernández Martínez, Ana Belén
Tipo de recurso: artículo
Fecha de publicación:2012
País:España
Institución:Universidad Francisco de Vitoria
Repositorio:DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Idioma:inglés
OAI Identifier:oai:ddfv.ufv.es:10641/5370
Acceso en línea:https://hdl.handle.net/10641/5370
Access Level:acceso abierto
Palabra clave:Traditional Chinese medicine
Chinese herbal medicine
Animal models
Cancer
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spelling MEDLINE-based assessment of animal studies on Chinese herbal medicine.Tejedor García, NoeliaGarcia Bermejo, LauraFernández Martínez, Ana BelénTraditional Chinese medicineChinese herbal medicineAnimal modelsCancerEthno-pharmacological relevance: The scientific proof and clinical validation of Chinese herbal medicine (CHM) require a rigorous approach that includes chemical standardization, biological assays, animal studies and clinical trials. Aim of the study: To assess the experimental design of animal studies on the activity of CHM by selection and scrutinizing of a series of papers in some major disease areas. Materials and methods: We have analyzed the English publications reported in MEDLINE (ISI web of knowledge). Results: Our data showed that (i) research of CHM during the last 10 years had been highly intensified and become more accessible worldwide through increased publications in English, although still most authors had Chinese names; (ii) English journals publishing animal research of CHM were comparable to those publishing animal studies of non-Chinese phytotherapy in terms of impact factor; and (iii) published data on authentication and quality control of CHM, as well as research design of animal studies were far from sufficient to meet the criteria needed to support their reproducibility and reliability. Conclusions and perspectives: The recent decade witnessed an increase in CHM research activities and CHM English publications. Based on common problems identified in publications on CHM animal studies, we have proposed a checklist that could help in preliminary selection of publications lacking the most common problems and thus would be useful for a quick search of reproducible CHM regimens that are likely to be effective in a given context. The second application of this checklist is to help avoid the most common problems when designing experiments.Elsevier20122012-01-0120122012-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10641/5370reponame:DDFV. Repositorio Institucional de la Universidad Francisco de Vitoriainstname:Universidad Francisco de VitoriaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ddfv.ufv.es:10641/53702026-06-11T12:44:57Z
dc.title.none.fl_str_mv MEDLINE-based assessment of animal studies on Chinese herbal medicine.
title MEDLINE-based assessment of animal studies on Chinese herbal medicine.
spellingShingle MEDLINE-based assessment of animal studies on Chinese herbal medicine.
Tejedor García, Noelia
Traditional Chinese medicine
Chinese herbal medicine
Animal models
Cancer
title_short MEDLINE-based assessment of animal studies on Chinese herbal medicine.
title_full MEDLINE-based assessment of animal studies on Chinese herbal medicine.
title_fullStr MEDLINE-based assessment of animal studies on Chinese herbal medicine.
title_full_unstemmed MEDLINE-based assessment of animal studies on Chinese herbal medicine.
title_sort MEDLINE-based assessment of animal studies on Chinese herbal medicine.
dc.creator.none.fl_str_mv Tejedor García, Noelia
Garcia Bermejo, Laura
Fernández Martínez, Ana Belén
author Tejedor García, Noelia
author_facet Tejedor García, Noelia
Garcia Bermejo, Laura
Fernández Martínez, Ana Belén
author_role author
author2 Garcia Bermejo, Laura
Fernández Martínez, Ana Belén
author2_role author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Traditional Chinese medicine
Chinese herbal medicine
Animal models
Cancer
topic Traditional Chinese medicine
Chinese herbal medicine
Animal models
Cancer
description Ethno-pharmacological relevance: The scientific proof and clinical validation of Chinese herbal medicine (CHM) require a rigorous approach that includes chemical standardization, biological assays, animal studies and clinical trials. Aim of the study: To assess the experimental design of animal studies on the activity of CHM by selection and scrutinizing of a series of papers in some major disease areas. Materials and methods: We have analyzed the English publications reported in MEDLINE (ISI web of knowledge). Results: Our data showed that (i) research of CHM during the last 10 years had been highly intensified and become more accessible worldwide through increased publications in English, although still most authors had Chinese names; (ii) English journals publishing animal research of CHM were comparable to those publishing animal studies of non-Chinese phytotherapy in terms of impact factor; and (iii) published data on authentication and quality control of CHM, as well as research design of animal studies were far from sufficient to meet the criteria needed to support their reproducibility and reliability. Conclusions and perspectives: The recent decade witnessed an increase in CHM research activities and CHM English publications. Based on common problems identified in publications on CHM animal studies, we have proposed a checklist that could help in preliminary selection of publications lacking the most common problems and thus would be useful for a quick search of reproducible CHM regimens that are likely to be effective in a given context. The second application of this checklist is to help avoid the most common problems when designing experiments.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01
2012
2012-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10641/5370
url https://hdl.handle.net/10641/5370
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname:Universidad Francisco de Vitoria
instname_str Universidad Francisco de Vitoria
reponame_str DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
collection DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
repository.name.fl_str_mv
repository.mail.fl_str_mv
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