Stable N-heterocyclic carbene (NHC)-palladium(0) complexes as active catalysts for olefin cyclopropanation reactions with ethyl diazoacetate

The Pd(0) complexes NHCPdLn (NHC = N-heterocyclic carbene ligand; L = styrene for n = 2 or PR3 for n = 1) efficiently catalyze the olefin cyclopropanation using ethyl diazoacetate (EDA) as the carbene source with activities that improve any other previous described catalytic system based on this met...

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Detalles Bibliográficos
Autores: Martín, Carmen, Molina González, Francisco, Álvarez, Eleuterio, Rodríguez Belderraín, Tomás
Tipo de recurso: artículo
Fecha de publicación:2011
País:España
Institución:Universidad de Huelva (UHU)
Repositorio:Arias Montano. Repositorio Institucional de la Universidad de Huelva
Idioma:inglés
OAI Identifier:oai:ariasmontano.uhu.es:10272/11567
Acceso en línea:http://hdl.handle.net/10272/11567
Access Level:acceso abierto
Palabra clave:Diazoester
Cyclopropanation
Homogeneous catalysis
Palladium
Descripción
Sumario:The Pd(0) complexes NHCPdLn (NHC = N-heterocyclic carbene ligand; L = styrene for n = 2 or PR3 for n = 1) efficiently catalyze the olefin cyclopropanation using ethyl diazoacetate (EDA) as the carbene source with activities that improve any other previous described catalytic system based on this metal. Mechanistic studies have shown that all those catalyst precursors deliver in solution the same catalytic species (IPr)Pd(sty), a 14e, unsaturated intermediate that further reacts with EDA to afford (IPr)Pd(=CHCO2Et)(sty), from which cyclopropane is formed.