Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome

Aim To compare the efficacy of transcutaneous tibial nerve stimulation (TTNS) with percutaneous tibial nerve stimulation (PTNS) regarding patient-reported outcomes measures, specifically quality-of-life (QoL) improvement and patient's treatment benefit, on symptoms associated with overactive bl...

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Autores: Ramírez-García, Inés, Kauffmann, Stéphanie, Blanco Ratto, Laia, Carralero-Martínez, Andrea, Sánchez-Ruiz, Emília
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Ramon Llull (URL)
Repositorio:DAU Arxiu Digital de la Universitat Ramon Llull
OAI Identifier:oai:dnet:dau_________::1a45da9cfa44e88e628bd26ebfbdb2b3
Acceso en línea:https://hdl.handle.net/20.500.14342/6381
https://doi.org/10.1002/nau.24554
Access Level:acceso abierto
Palabra clave:OAB-q-SF
Bufeta hiperactiva
PTNS
Qualitat de vida
Estimulació eléctrica
Nervi tibial
Escala de beneficis del tractament
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spelling Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndromeRamírez-García, InésKauffmann, StéphanieBlanco Ratto, LaiaCarralero-Martínez, AndreaSánchez-Ruiz, EmíliaOAB-q-SFBufeta hiperactivaPTNSQualitat de vidaEstimulació eléctricaNervi tibialEscala de beneficis del tractamentAim To compare the efficacy of transcutaneous tibial nerve stimulation (TTNS) with percutaneous tibial nerve stimulation (PTNS) regarding patient-reported outcomes measures, specifically quality-of-life (QoL) improvement and patient's treatment benefit, on symptoms associated with overactive bladder (OAB). Methods Patients with refractory OAB symptoms and detrusor overactivity were randomized to receive TTNS or PTNS for 12 weeks. Data from self-report OAB questionnaire short form (q-SF) and incontinence (I)-QoL questionnaires were collected pretreatment and at Weeks 6 and 12. Patients’ self-perceived benefits on symptoms (treatment benefit scale, TBS) were also gathered. Mean change in scores within and between groups were estimated. Results Sixty-eight adult patients (67.6% women) were included in the intention to treat analysis. Of those, 61 completed all questionnaires and were analyzed as per protocol. Statistically significant improvements in OAB-q-SF and I-QoL between baseline and end-of-treatment scores were observed in both TTNS and PTNS groups (p < .001), being the differences much higher than the minimal important difference in both questionnaires. The scores of the OAB-q-SF scales (symptoms bother and health-related QoL) showed no statistically significant differences between the two groups. Similarly, the differences regarding the I-QoL questionnaire were statistically nonsignificant either (p = .607). When assessing the treatment benefit on symptoms, TBS responses between groups showed no statistical differences. Conclusion A significant improvement of QoL was observed in both TTNS and PTNS groups. However, no patient-reported outcomes measures scores support a difference between the two groups. Therefore, these findings along with TTNS ease of application and less invasiveness may lead to an increased indication of this technique for OAB.info:eu-repo/semantics/acceptedVersionWiley Online LibraryUniversitat Ramon Llull. Facultat de Ciències de la Salut BlanquernaGrup de Recerca Global Research on Wellbeing - GRoW2026202620202021info:eu-repo/semantics/article8 p.application/pdfhttps://hdl.handle.net/20.500.14342/6381https://doi.org/10.1002/nau.24554reponame:DAU Arxiu Digital de la Universitat Ramon Llullinstname:Universitat Ramon Llull (URL)InglésNeurourology and urodynamics, 2021, 40(1), 295-302© Wiley PeriodicalsAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:dnet:dau_________::1a45da9cfa44e88e628bd26ebfbdb2b32026-06-21T06:40:37Z
dc.title.none.fl_str_mv Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
title Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
spellingShingle Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
Ramírez-García, Inés
OAB-q-SF
Bufeta hiperactiva
PTNS
Qualitat de vida
Estimulació eléctrica
Nervi tibial
Escala de beneficis del tractament
title_short Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
title_full Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
title_fullStr Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
title_full_unstemmed Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
title_sort Patient‐reported outcomes in the setting of a randomized control trial on the efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome
dc.creator.none.fl_str_mv Ramírez-García, Inés
Kauffmann, Stéphanie
Blanco Ratto, Laia
Carralero-Martínez, Andrea
Sánchez-Ruiz, Emília
author Ramírez-García, Inés
author_facet Ramírez-García, Inés
Kauffmann, Stéphanie
Blanco Ratto, Laia
Carralero-Martínez, Andrea
Sánchez-Ruiz, Emília
author_role author
author2 Kauffmann, Stéphanie
Blanco Ratto, Laia
Carralero-Martínez, Andrea
Sánchez-Ruiz, Emília
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universitat Ramon Llull. Facultat de Ciències de la Salut Blanquerna
Grup de Recerca Global Research on Wellbeing - GRoW
dc.subject.none.fl_str_mv OAB-q-SF
Bufeta hiperactiva
PTNS
Qualitat de vida
Estimulació eléctrica
Nervi tibial
Escala de beneficis del tractament
topic OAB-q-SF
Bufeta hiperactiva
PTNS
Qualitat de vida
Estimulació eléctrica
Nervi tibial
Escala de beneficis del tractament
description Aim To compare the efficacy of transcutaneous tibial nerve stimulation (TTNS) with percutaneous tibial nerve stimulation (PTNS) regarding patient-reported outcomes measures, specifically quality-of-life (QoL) improvement and patient's treatment benefit, on symptoms associated with overactive bladder (OAB). Methods Patients with refractory OAB symptoms and detrusor overactivity were randomized to receive TTNS or PTNS for 12 weeks. Data from self-report OAB questionnaire short form (q-SF) and incontinence (I)-QoL questionnaires were collected pretreatment and at Weeks 6 and 12. Patients’ self-perceived benefits on symptoms (treatment benefit scale, TBS) were also gathered. Mean change in scores within and between groups were estimated. Results Sixty-eight adult patients (67.6% women) were included in the intention to treat analysis. Of those, 61 completed all questionnaires and were analyzed as per protocol. Statistically significant improvements in OAB-q-SF and I-QoL between baseline and end-of-treatment scores were observed in both TTNS and PTNS groups (p < .001), being the differences much higher than the minimal important difference in both questionnaires. The scores of the OAB-q-SF scales (symptoms bother and health-related QoL) showed no statistically significant differences between the two groups. Similarly, the differences regarding the I-QoL questionnaire were statistically nonsignificant either (p = .607). When assessing the treatment benefit on symptoms, TBS responses between groups showed no statistical differences. Conclusion A significant improvement of QoL was observed in both TTNS and PTNS groups. However, no patient-reported outcomes measures scores support a difference between the two groups. Therefore, these findings along with TTNS ease of application and less invasiveness may lead to an increased indication of this technique for OAB.
publishDate 2020
dc.date.none.fl_str_mv 2020
2021
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14342/6381
https://doi.org/10.1002/nau.24554
url https://hdl.handle.net/20.500.14342/6381
https://doi.org/10.1002/nau.24554
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Neurourology and urodynamics, 2021, 40(1), 295-302
dc.rights.none.fl_str_mv © Wiley Periodicals
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © Wiley Periodicals
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 8 p.
application/pdf
dc.publisher.none.fl_str_mv Wiley Online Library
publisher.none.fl_str_mv Wiley Online Library
dc.source.none.fl_str_mv reponame:DAU Arxiu Digital de la Universitat Ramon Llull
instname:Universitat Ramon Llull (URL)
instname_str Universitat Ramon Llull (URL)
reponame_str DAU Arxiu Digital de la Universitat Ramon Llull
collection DAU Arxiu Digital de la Universitat Ramon Llull
repository.name.fl_str_mv
repository.mail.fl_str_mv
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