Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata

A procedure based on microwave assisted extraction for the determination of 6 pharmaceuticals in samples of Lavandula dentata, Salicornia ramosissima and Juncus sp. by liquid chromatography-quadrupole time of flight mass spectrometry (LC-QTOF/MS) was optimized and validated. Best results were obtain...

Descripción completa

Detalles Bibliográficos
Autores: Barreales Suárez, Sofía, Callejón Mochón, Manuel, Azoulay, Stéphane, Bello López, Miguel Ángel, Fernández Torres, Rut
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2018
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/153250
Acceso en línea:https://hdl.handle.net/11441/153250
https://doi.org/10.1016/j.scitotenv.2017.11.244
Access Level:acceso abierto
Palabra clave:Juncus
Lavandula dentata
Liquid chromatography quadrupole time-of-flight
Microwave extraction
Pharmaceuticals
Salicornia
id ES_4d5d0a0ccd805bf414eb7321fbbcced8
oai_identifier_str oai:idus.us.es:11441/153250
network_acronym_str ES
network_name_str España
repository_id_str
spelling Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula DentataBarreales Suárez, SofíaCallejón Mochón, ManuelAzoulay, StéphaneBello López, Miguel ÁngelFernández Torres, RutJuncusLavandula dentataLiquid chromatography quadrupole time-of-flightMicrowave extractionPharmaceuticalsSalicorniaA procedure based on microwave assisted extraction for the determination of 6 pharmaceuticals in samples of Lavandula dentata, Salicornia ramosissima and Juncus sp. by liquid chromatography-quadrupole time of flight mass spectrometry (LC-QTOF/MS) was optimized and validated. Best results were obtained using microwave assisted extraction of 1.0 g of homogeneous lyophilized samples and 5 mL of a mixture ACN:H2O (1:1 v/v) as extracting solvent. Analytical recoveries ranged from 60 to 107% with relative standard deviation (RSD) lower than 15%. Limits of quantitation (LOQ) for the 6 pharmaceuticals flumequine (FLM), carbamazepine (CBZ), ciprofloxacin (CPR), enrofloxacin (ENR), diclofenac (DCL), and ibuprofen (IBU) were in the range 20.8–125 ng g− 1. The method was satisfactory applied for an uptake study in Lavandula dentata samples finding quantifying concentrations of FLM and CBZ in roots, leaf and stem.Ministerio de Educación, Cultura y Deporte CTM2015-67902-C-1-PEuropean Commission. Fondo Europeo de Desarrollo Regional UNSE10-1E-429ElsevierQuímica AnalíticaMinisterio de Educación, Cultura y Deporte (MECD). EspañaEuropean Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER)2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/153250https://doi.org/10.1016/j.scitotenv.2017.11.244reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésScience of the Total Environment, 622-623, 655-663.CTM2015-67902-C-1-PUNSE10-1E-429https://doi.org/10.1016/j.scitotenv.2017.11.244info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1532502026-06-17T12:51:07Z
dc.title.none.fl_str_mv Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
title Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
spellingShingle Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
Barreales Suárez, Sofía
Juncus
Lavandula dentata
Liquid chromatography quadrupole time-of-flight
Microwave extraction
Pharmaceuticals
Salicornia
title_short Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
title_full Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
title_fullStr Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
title_full_unstemmed Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
title_sort Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
dc.creator.none.fl_str_mv Barreales Suárez, Sofía
Callejón Mochón, Manuel
Azoulay, Stéphane
Bello López, Miguel Ángel
Fernández Torres, Rut
author Barreales Suárez, Sofía
author_facet Barreales Suárez, Sofía
Callejón Mochón, Manuel
Azoulay, Stéphane
Bello López, Miguel Ángel
Fernández Torres, Rut
author_role author
author2 Callejón Mochón, Manuel
Azoulay, Stéphane
Bello López, Miguel Ángel
Fernández Torres, Rut
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Química Analítica
Ministerio de Educación, Cultura y Deporte (MECD). España
European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER)
dc.subject.none.fl_str_mv Juncus
Lavandula dentata
Liquid chromatography quadrupole time-of-flight
Microwave extraction
Pharmaceuticals
Salicornia
topic Juncus
Lavandula dentata
Liquid chromatography quadrupole time-of-flight
Microwave extraction
Pharmaceuticals
Salicornia
description A procedure based on microwave assisted extraction for the determination of 6 pharmaceuticals in samples of Lavandula dentata, Salicornia ramosissima and Juncus sp. by liquid chromatography-quadrupole time of flight mass spectrometry (LC-QTOF/MS) was optimized and validated. Best results were obtained using microwave assisted extraction of 1.0 g of homogeneous lyophilized samples and 5 mL of a mixture ACN:H2O (1:1 v/v) as extracting solvent. Analytical recoveries ranged from 60 to 107% with relative standard deviation (RSD) lower than 15%. Limits of quantitation (LOQ) for the 6 pharmaceuticals flumequine (FLM), carbamazepine (CBZ), ciprofloxacin (CPR), enrofloxacin (ENR), diclofenac (DCL), and ibuprofen (IBU) were in the range 20.8–125 ng g− 1. The method was satisfactory applied for an uptake study in Lavandula dentata samples finding quantifying concentrations of FLM and CBZ in roots, leaf and stem.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/153250
https://doi.org/10.1016/j.scitotenv.2017.11.244
url https://hdl.handle.net/11441/153250
https://doi.org/10.1016/j.scitotenv.2017.11.244
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Science of the Total Environment, 622-623, 655-663.
CTM2015-67902-C-1-P
UNSE10-1E-429
https://doi.org/10.1016/j.scitotenv.2017.11.244
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869407686972407808
score 15,300719

Similares en LA Referencia