Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting
To analyse the clinical characteristics and management of patients with non-valvular atrial fibrillation (NVAF) treated with direct oral anticoagulants (DOAC). Observational, cross-sectional and multicentre study. Autonomous Communities in which the general practitioner can prescribe DOAC (n = 9). T...
| Autores: | , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | español |
| OAI Identifier: | oai:ddd.uab.cat:287811 |
| Acceso en línea: | https://ddd.uab.cat/record/287811 https://dx.doi.org/urn:doi:10.1016/j.aprim.2017.05.009 |
| Access Level: | acceso abierto |
| Palabra clave: | Anticoagulación Anticoagulantes orales de acción directa Anticoagulation Atención primaria Direct oral anticoagulants Fibrilación auricular no valvular Non-valvular atrial fibrillation Primary care |
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Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care settingThe SILVER-AP studyPerfil clínico de pacientes con fibrilación auricular tratados con anticoagulantes orales de acción directa atendidos en atención primariade la Figuera, Mariano|||0000-0003-2533-2135Cinza, SergioMarín, NuriaEgocheaga, IsabelPrieto, Miguel AngelAnticoagulaciónAnticoagulantes orales de acción directaAnticoagulationAtención primariaDirect oral anticoagulantsFibrilación auricular no valvularNon-valvular atrial fibrillationPrimary careTo analyse the clinical characteristics and management of patients with non-valvular atrial fibrillation (NVAF) treated with direct oral anticoagulants (DOAC). Observational, cross-sectional and multicentre study. Autonomous Communities in which the general practitioner can prescribe DOAC (n = 9). The study included a total of 790 patients on chronic treatment with anticoagulants, and on whom therapy was changed, as well as being currently on treatment with DOAC for at least for 3 months. A record was made of the sociodemographic and clinical management date. Mean age was 78.6 ± 8.4 years, and 50.5% of patients were men. Mean CHADS score was 2.6 ± 1.2, mean CHADS-VASc score was 4.3 ± 1.6, and the mean HAS-BLED score was 2.3 ± 1.0. Mean duration of treatment with DOAC was 15.8 ± 12.5 months. Rivaroxaban was the DOAC most frequently prescribed (57.8%), followed by dabigatran (23.7%), and apixaban (18.5%). Of the patients receiving rivaroxaban, 70.2% were taking the dose of 20 mg/daily. Of the patients receiving dabigatran, 41.7% were taking the dose of 150 mg twice daily, and in the case of apixaban, 56.2% were taking the dose of 5 mg twice daily. Satisfaction (ACTS Burdens scale 52.0 ± 7.2 and ACTS Benefits scale 12.1 ± 2.2), and therapeutic adherence (97.8% of patients took their medication regularly) with DOAC were high. Patients treated with DOAC in Spain have a high thromboembolic risk. A significant proportion of patients receive a lower dose of DOAC than that recommended according to their clinical profile. Satisfaction and medication adherence are high.Universitat Autònoma de Barcelona 22018-01-0120182018-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/287811https://dx.doi.org/urn:doi:10.1016/j.aprim.2017.05.009reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaEspañolspaopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2878112026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting The SILVER-AP study Perfil clínico de pacientes con fibrilación auricular tratados con anticoagulantes orales de acción directa atendidos en atención primaria |
| title |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting |
| spellingShingle |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting de la Figuera, Mariano|||0000-0003-2533-2135 Anticoagulación Anticoagulantes orales de acción directa Anticoagulation Atención primaria Direct oral anticoagulants Fibrilación auricular no valvular Non-valvular atrial fibrillation Primary care |
| title_short |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting |
| title_full |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting |
| title_fullStr |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting |
| title_full_unstemmed |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting |
| title_sort |
Clinical characteristics of patients with atrial fibrillation treated with direct oral anticoagulants attended in primary care setting |
| dc.creator.none.fl_str_mv |
de la Figuera, Mariano|||0000-0003-2533-2135 Cinza, Sergio Marín, Nuria Egocheaga, Isabel Prieto, Miguel Angel |
| author |
de la Figuera, Mariano|||0000-0003-2533-2135 |
| author_facet |
de la Figuera, Mariano|||0000-0003-2533-2135 Cinza, Sergio Marín, Nuria Egocheaga, Isabel Prieto, Miguel Angel |
| author_role |
author |
| author2 |
Cinza, Sergio Marín, Nuria Egocheaga, Isabel Prieto, Miguel Angel |
| author2_role |
author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
Anticoagulación Anticoagulantes orales de acción directa Anticoagulation Atención primaria Direct oral anticoagulants Fibrilación auricular no valvular Non-valvular atrial fibrillation Primary care |
| topic |
Anticoagulación Anticoagulantes orales de acción directa Anticoagulation Atención primaria Direct oral anticoagulants Fibrilación auricular no valvular Non-valvular atrial fibrillation Primary care |
| description |
To analyse the clinical characteristics and management of patients with non-valvular atrial fibrillation (NVAF) treated with direct oral anticoagulants (DOAC). Observational, cross-sectional and multicentre study. Autonomous Communities in which the general practitioner can prescribe DOAC (n = 9). The study included a total of 790 patients on chronic treatment with anticoagulants, and on whom therapy was changed, as well as being currently on treatment with DOAC for at least for 3 months. A record was made of the sociodemographic and clinical management date. Mean age was 78.6 ± 8.4 years, and 50.5% of patients were men. Mean CHADS score was 2.6 ± 1.2, mean CHADS-VASc score was 4.3 ± 1.6, and the mean HAS-BLED score was 2.3 ± 1.0. Mean duration of treatment with DOAC was 15.8 ± 12.5 months. Rivaroxaban was the DOAC most frequently prescribed (57.8%), followed by dabigatran (23.7%), and apixaban (18.5%). Of the patients receiving rivaroxaban, 70.2% were taking the dose of 20 mg/daily. Of the patients receiving dabigatran, 41.7% were taking the dose of 150 mg twice daily, and in the case of apixaban, 56.2% were taking the dose of 5 mg twice daily. Satisfaction (ACTS Burdens scale 52.0 ± 7.2 and ACTS Benefits scale 12.1 ± 2.2), and therapeutic adherence (97.8% of patients took their medication regularly) with DOAC were high. Patients treated with DOAC in Spain have a high thromboembolic risk. A significant proportion of patients receive a lower dose of DOAC than that recommended according to their clinical profile. Satisfaction and medication adherence are high. |
| publishDate |
2018 |
| dc.date.none.fl_str_mv |
2 2018-01-01 2018 2018-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/287811 https://dx.doi.org/urn:doi:10.1016/j.aprim.2017.05.009 |
| url |
https://ddd.uab.cat/record/287811 https://dx.doi.org/urn:doi:10.1016/j.aprim.2017.05.009 |
| dc.language.none.fl_str_mv |
Español spa |
| language_invalid_str_mv |
Español |
| language |
spa |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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