Aluminium Catalysed Oxazolidinone Synthesis and their Conversion into Functional Non-Symmetrical Ureas
An efficient and practical aluminium-catalysed approach towards a range of functional oxazolidinones is reported. The method is based on cheap and readily available starting materials including terminal and internal (bicyclic) epoxides and phenylcarbamate. The oxazolidinones serve as highly useful s...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2015 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2072/356052 |
| Acceso en línea: | http://hdl.handle.net/2072/356052 https://doi.org/10.1002/adsc.201500635 |
| Access Level: | acceso abierto |
| Palabra clave: | 54 |
| Sumario: | An efficient and practical aluminium-catalysed approach towards a range of functional oxazolidinones is reported. The method is based on cheap and readily available starting materials including terminal and internal (bicyclic) epoxides and phenylcarbamate. The oxazolidinones serve as highly useful synthons for the high yield preparation of nonsymmetrical ureas by nucleophilic ring-opening affording the targeted urea compounds with excellent functional group diversity, and high regio-selectivity and isolated yields up to >99%. |
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