Compositional covariance shrinkage and regularised partial correlations

We propose an estimation procedure for covariation in wide compositional data sets. For compositions, widely-used logratio variables are interdependent due to a common reference. Logratio uncorrelated compositions are linearly independent before the unitsum constraint is imposed. We show how they ar...

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Detalles Bibliográficos
Autores: Jin, Suzanne|||0000-0001-6991-8002, Notredame, Cedric|||0000-0003-1461-0988, Erb, Ionas|||0000-0002-2331-9714
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:285319
Acceso en línea:https://ddd.uab.cat/record/285319
https://dx.doi.org/urn:doi:10.57645/20.8080.02.8
Access Level:acceso abierto
Palabra clave:Compositional covariance structure
Logratio analysis
Partial correlation
James-Stein shrinkage
Descripción
Sumario:We propose an estimation procedure for covariation in wide compositional data sets. For compositions, widely-used logratio variables are interdependent due to a common reference. Logratio uncorrelated compositions are linearly independent before the unitsum constraint is imposed. We show how they are used to construct bespoke shrinkage targets for logratio covariance matrices and test a simple procedure for partial correlation estimates on both a simulated and a single-cell gene expression data set. For the underlying counts, different zero imputations are evaluated. The partial correlation induced by the closure is derived analytically. Data and code are available from GitHub.