Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes

This article belongs to the Special Issue Selected Papers from 11th International Workshop on Anthocyanins and Betalains (IWA&B 2024).

Detalles Bibliográficos
Autores: Gómez-López, Iván, Eseberri, Itziar, Krisa, Stéphanie, Cano, M. Pilar, Portillo, María P.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/372772
Acceso en línea:http://hdl.handle.net/10261/372772
Access Level:acceso abierto
Palabra clave:3T3-L1 pre-adipocytes
Opuntia stricta var. dillenii
Adipogenesis
Adiponectin
Betalains
Phenolic compounds
Triacylglycerol
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spelling Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytesGómez-López, IvánEseberri, ItziarKrisa, StéphanieCano, M. PilarPortillo, María P.3T3-L1 pre-adipocytesOpuntia stricta var. dilleniiAdipogenesisAdiponectinBetalainsPhenolic compoundsTriacylglycerolThis article belongs to the Special Issue Selected Papers from 11th International Workshop on Anthocyanins and Betalains (IWA&B 2024).Opuntia stricta var. dillenii, a member of the Cactaceae family, produces a fruit known as prickly pear. This fruit is rich in bioactive compounds, including betalains and phenolic compounds, which play an important role in health promotion due to their antioxidant and anti-inflammatory properties. This study aims to investigate the impact of prickly pear extracts obtained from the whole fruit, peel, pulp, and an industrial by-product (bagasse) on the differentiation of 3T3-L1 pre-adipocytes. During the differentiation process, 3T3-L1 pre-adipocytes were treated with prickly pear extracts at concentrations ranging from 10 to 100 μg/mL from day 0 to day 8 post-induction. Moreover, the potential mechanisms justifying the observed effects were assessed by RT-PCR. All extracts led to an increase in both triacylglycerol accumulation and cell number. In conclusion, the analysed extracts demonstrated adipogenic effects in 3T3-L1 maturing pre-adipocytes by increasing the expression of the c/ebp-β, srebf-1, and c/ebp-α genes. Additionally, a potential anti-inflammatory effect was observed through the upregulation of adiponectin.This research was supported by grants PID2020-118300RB-C21 and PID2020-118300RB-C22 funded by the Spanish Science and Innovation Ministry (MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”).Peer reviewedMultidisciplinary Digital Publishing InstituteAgencia Estatal de Investigación (España)Ministerio de Ciencia, Innovación y Universidades (España)European CommissionConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242024info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/372772reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-118300RB-C21info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-118300RB-C22Gómez-López, Iván; Eseberri, Itziar; Krisa, Stéphanie; Cano, M. Pilar; Portillo, María P.; 2024; Supplementary Materials: Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes [Dataset]; Multidisciplinary Digital Publishing Institute; https://doi.org/10.3390/plants13212967https://doi.org/10.3390/plants13212967Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3727722026-05-22T06:33:51Z
dc.title.none.fl_str_mv Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
title Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
spellingShingle Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
Gómez-López, Iván
3T3-L1 pre-adipocytes
Opuntia stricta var. dillenii
Adipogenesis
Adiponectin
Betalains
Phenolic compounds
Triacylglycerol
title_short Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
title_full Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
title_fullStr Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
title_full_unstemmed Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
title_sort Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes
dc.creator.none.fl_str_mv Gómez-López, Iván
Eseberri, Itziar
Krisa, Stéphanie
Cano, M. Pilar
Portillo, María P.
author Gómez-López, Iván
author_facet Gómez-López, Iván
Eseberri, Itziar
Krisa, Stéphanie
Cano, M. Pilar
Portillo, María P.
author_role author
author2 Eseberri, Itziar
Krisa, Stéphanie
Cano, M. Pilar
Portillo, María P.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Agencia Estatal de Investigación (España)
Ministerio de Ciencia, Innovación y Universidades (España)
European Commission
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv 3T3-L1 pre-adipocytes
Opuntia stricta var. dillenii
Adipogenesis
Adiponectin
Betalains
Phenolic compounds
Triacylglycerol
topic 3T3-L1 pre-adipocytes
Opuntia stricta var. dillenii
Adipogenesis
Adiponectin
Betalains
Phenolic compounds
Triacylglycerol
description This article belongs to the Special Issue Selected Papers from 11th International Workshop on Anthocyanins and Betalains (IWA&B 2024).
publishDate 2024
dc.date.none.fl_str_mv 2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/372772
url http://hdl.handle.net/10261/372772
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-118300RB-C21
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-118300RB-C22
Gómez-López, Iván; Eseberri, Itziar; Krisa, Stéphanie; Cano, M. Pilar; Portillo, María P.; 2024; Supplementary Materials: Effects of Opuntia stricta var. dillenii extracts obtained from prickly pear and an industrial by-product on maturing pre-adipocytes [Dataset]; Multidisciplinary Digital Publishing Institute; https://doi.org/10.3390/plants13212967
https://doi.org/10.3390/plants13212967
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
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