Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom

[EN] A great deal of current research is directed to finding a way to minimize thermal injury in the esophagus during radiofrequency catheter ablation of the atrium. A recent clinical study employing a cooling intraesophageal balloon reported a reduction of the temperature in the esophageal lumen. H...

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Autores: Lequerica, Juan L., Herrero, Maria, Melecio, Lemuel, Hornero, Fernando, Berjano, Enrique|||0000-0002-3247-2665
Tipo de recurso: artículo
Fecha de publicación:2008
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/99714
Acceso en línea:https://riunet.upv.es/handle/10251/99714
Access Level:acceso abierto
Palabra clave:TECNOLOGIA ELECTRONICA
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spelling Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantomLequerica, Juan L.Herrero, MariaMelecio, LemuelHornero, FernandoBerjano, Enrique|||0000-0002-3247-2665TECNOLOGIA ELECTRONICA[EN] A great deal of current research is directed to finding a way to minimize thermal injury in the esophagus during radiofrequency catheter ablation of the atrium. A recent clinical study employing a cooling intraesophageal balloon reported a reduction of the temperature in the esophageal lumen. However, it could not be determined whether the deeper muscular layer of the esophagus was cooled enough to prevent injury. We built a model based on an agar phantom in order to experimentally study the thermal behavior of this balloon by measuring the temperature not only on the balloon, but also at a hypothetical point between the esophageal lumen and myocardium (2 mm distant). Controlled temperature (55 degrees C) ablations were conducted for 120 s. The results showed that (1) the cooling balloon provides a reduction in the final temperature reached, both on the balloon surface and at a distance of 2 mm; (2) coolant temperature has a significant effect on the temperature measured at 2 mm from the esophageal lumen (it has a less effect on the temperature measured on the balloon surface) and (3) the pre- cooling period has a significant effect on the temperature measured on the balloon surface (the effect on the temperaturemeasured 2mmaway is small). The results were in good agreement with those obtained in a previous clinical study. The study suggests that the cooling balloon gives thermal protection to the esophagus when a minimum pre- cooling period of 2 min is programmed at a coolant temperature of 5 degrees C or less.We would like to thank the R+D+i Linguistic Assistance Office at the Technical Universityof Valencia for their help in revising this paper. This work was partially financially supported by the ‘Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica del Ministerio de Educación y Ciencia of Spain (TEC 2005-04199/TCM) and by an R&D contract (CSIC-20060633) between Edwards Life science Ltd. and the Spanish Council for ScientificResearch (CSIC).IOP PublishingDepartamento de Ingeniería ElectrónicaEscuela Técnica Superior de Ingeniería Aeroespacial y Diseño IndustrialBiosignals & Minimally Invasive Technologies-BioMITMinisterio de Educación y CienciaConsejo Superior de Investigaciones CientíficasRepositorio Institucional de la Universitat Politècnica de València Riunet20082008-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://riunet.upv.es/handle/10251/99714reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengMinisterio de Educación y Ciencia https://doi.org/10.13039/501100008743 TEC2005-04199 MODELOS TEORICOS Y COMPUTACION AVANZADA EN EL ESTUDIO DE SEÑALES BIOELECTRICAS EN CELULAS Y TEJIDOS. IMPLICACIONES EN EL ANALISIS DE ARRITMIAS CARDIACAS, ELECTROESTIMULACION Y ABLACION POR RADIOFRECUENCIAComisión Sectorial de Investigación Científica, Uruguay https://doi.org/10.13039/501100003339 20060633open accesshttp://purl.org/coar/access_right/c_abf2Reserva de todos los derechoshttp://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/997142026-06-13T07:49:27Z
dc.title.none.fl_str_mv Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
title Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
spellingShingle Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
Lequerica, Juan L.
TECNOLOGIA ELECTRONICA
title_short Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
title_full Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
title_fullStr Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
title_full_unstemmed Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
title_sort Cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: Experimental study based on an agar phantom
dc.creator.none.fl_str_mv Lequerica, Juan L.
Herrero, Maria
Melecio, Lemuel
Hornero, Fernando
Berjano, Enrique|||0000-0002-3247-2665
author Lequerica, Juan L.
author_facet Lequerica, Juan L.
Herrero, Maria
Melecio, Lemuel
Hornero, Fernando
Berjano, Enrique|||0000-0002-3247-2665
author_role author
author2 Herrero, Maria
Melecio, Lemuel
Hornero, Fernando
Berjano, Enrique|||0000-0002-3247-2665
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Departamento de Ingeniería Electrónica
Escuela Técnica Superior de Ingeniería Aeroespacial y Diseño Industrial
Biosignals & Minimally Invasive Technologies-BioMIT
Ministerio de Educación y Ciencia
Consejo Superior de Investigaciones Científicas
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv TECNOLOGIA ELECTRONICA
topic TECNOLOGIA ELECTRONICA
description [EN] A great deal of current research is directed to finding a way to minimize thermal injury in the esophagus during radiofrequency catheter ablation of the atrium. A recent clinical study employing a cooling intraesophageal balloon reported a reduction of the temperature in the esophageal lumen. However, it could not be determined whether the deeper muscular layer of the esophagus was cooled enough to prevent injury. We built a model based on an agar phantom in order to experimentally study the thermal behavior of this balloon by measuring the temperature not only on the balloon, but also at a hypothetical point between the esophageal lumen and myocardium (2 mm distant). Controlled temperature (55 degrees C) ablations were conducted for 120 s. The results showed that (1) the cooling balloon provides a reduction in the final temperature reached, both on the balloon surface and at a distance of 2 mm; (2) coolant temperature has a significant effect on the temperature measured at 2 mm from the esophageal lumen (it has a less effect on the temperature measured on the balloon surface) and (3) the pre- cooling period has a significant effect on the temperature measured on the balloon surface (the effect on the temperaturemeasured 2mmaway is small). The results were in good agreement with those obtained in a previous clinical study. The study suggests that the cooling balloon gives thermal protection to the esophagus when a minimum pre- cooling period of 2 min is programmed at a coolant temperature of 5 degrees C or less.
publishDate 2008
dc.date.none.fl_str_mv 2008
2008-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/99714
url https://riunet.upv.es/handle/10251/99714
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Educación y Ciencia https://doi.org/10.13039/501100008743 TEC2005-04199 MODELOS TEORICOS Y COMPUTACION AVANZADA EN EL ESTUDIO DE SEÑALES BIOELECTRICAS EN CELULAS Y TEJIDOS. IMPLICACIONES EN EL ANALISIS DE ARRITMIAS CARDIACAS, ELECTROESTIMULACION Y ABLACION POR RADIOFRECUENCIA
Comisión Sectorial de Investigación Científica, Uruguay https://doi.org/10.13039/501100003339 20060633
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv IOP Publishing
publisher.none.fl_str_mv IOP Publishing
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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