Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy

This review emphasises the importance of opioid monitoring in clinical practice and advocates for a personalised approach based on pharmacogenetics. Beyond effectively managing pain, meticulous oversight is required to address concerns about side effects, specially due to opioidcrisis- related abuse...

ver descrição completa

Detalhes bibliográficos
Autores: Rosendo, Luana M., Rosado, Tiago, Zandonai, Thomas, Rincon, Karem, Peiró, Ana, Barroso, Mário, Gallardo, Eugenia
Formato: artículo
Fecha de publicación:2024
País:España
Recursos:Universidad Miguel Hernández de Elche
Repositorio:REDIUMH. Depósito Digital de la UMH
OAI Identifier:oai:dspace.umh.es:11000/32545
Acesso em linha:https://hdl.handle.net/11000/32545
Access Level:acceso abierto
Palavra-chave:chronic pain
opioids
monitoring
pharmacogenetics
clinical implications
CDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiología
id ES_4c21d1e73e9133d2cc7084df76d5af7d
oai_identifier_str oai:dspace.umh.es:11000/32545
network_acronym_str ES
network_name_str España
repository_id_str
spelling Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for TherapyRosendo, Luana M.Rosado, TiagoZandonai, ThomasRincon, KaremPeiró, AnaBarroso, MárioGallardo, Eugeniachronic painopioidsmonitoringpharmacogeneticsclinical implicationsCDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. RadiologíaThis review emphasises the importance of opioid monitoring in clinical practice and advocates for a personalised approach based on pharmacogenetics. Beyond effectively managing pain, meticulous oversight is required to address concerns about side effects, specially due to opioidcrisis- related abuse and dependence. Various monitoring techniques, along with pharmacogenetic considerations, are critical for personalising treatment and optimising pain relief while reducing misuse and addiction risks. Future perspectives reveal both opportunities and challenges, with advances in analytical technologies holding promise for increasing monitoring efficiency. The integration of pharmacogenetics has the potential to transform pain management by allowing for a precise prediction of drug responses. Nevertheless, challenges such as prominent pharmacogenetic testing and guideline standardisation persist. Collaborative efforts are critical for transforming scientific advances into tangible improvements in patient care. Standardised protocols and interdisciplinary collaboration are required to ensure consistent and evidence-based opioid monitoring. Future research should look into the long-term effects of opioid therapy, as well as the impact of genetic factors on individual responses, to help guide personalised treatment plans and reduce adverse events. Lastly, embracing innovation and collaboration can improve the standard of care in chronic pain management by striking a balance between pain relief and patient safetyMDPIDepartamentos de la UMH::Farmacología, Pediatría y Química Orgánica202420242024info:eu-repo/semantics/articleapplication/pdf32application/pdfhttps://hdl.handle.net/11000/32545reponame:REDIUMH. Depósito Digital de la UMHinstname:Universidad Miguel Hernández de ElcheIngléshttps://doi.org/10.3390/ijms25115925info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/oai:dspace.umh.es:11000/325452026-05-27T13:36:21Z
dc.title.none.fl_str_mv Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
title Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
spellingShingle Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
Rosendo, Luana M.
chronic pain
opioids
monitoring
pharmacogenetics
clinical implications
CDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiología
title_short Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
title_full Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
title_fullStr Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
title_full_unstemmed Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
title_sort Opioid Monitoring in Clinical Settings: Strategies and Implications of Tailored Approaches for Therapy
dc.creator.none.fl_str_mv Rosendo, Luana M.
Rosado, Tiago
Zandonai, Thomas
Rincon, Karem
Peiró, Ana
Barroso, Mário
Gallardo, Eugenia
author Rosendo, Luana M.
author_facet Rosendo, Luana M.
Rosado, Tiago
Zandonai, Thomas
Rincon, Karem
Peiró, Ana
Barroso, Mário
Gallardo, Eugenia
author_role author
author2 Rosado, Tiago
Zandonai, Thomas
Rincon, Karem
Peiró, Ana
Barroso, Mário
Gallardo, Eugenia
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Departamentos de la UMH::Farmacología, Pediatría y Química Orgánica
dc.subject.none.fl_str_mv chronic pain
opioids
monitoring
pharmacogenetics
clinical implications
CDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiología
topic chronic pain
opioids
monitoring
pharmacogenetics
clinical implications
CDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiología
description This review emphasises the importance of opioid monitoring in clinical practice and advocates for a personalised approach based on pharmacogenetics. Beyond effectively managing pain, meticulous oversight is required to address concerns about side effects, specially due to opioidcrisis- related abuse and dependence. Various monitoring techniques, along with pharmacogenetic considerations, are critical for personalising treatment and optimising pain relief while reducing misuse and addiction risks. Future perspectives reveal both opportunities and challenges, with advances in analytical technologies holding promise for increasing monitoring efficiency. The integration of pharmacogenetics has the potential to transform pain management by allowing for a precise prediction of drug responses. Nevertheless, challenges such as prominent pharmacogenetic testing and guideline standardisation persist. Collaborative efforts are critical for transforming scientific advances into tangible improvements in patient care. Standardised protocols and interdisciplinary collaboration are required to ensure consistent and evidence-based opioid monitoring. Future research should look into the long-term effects of opioid therapy, as well as the impact of genetic factors on individual responses, to help guide personalised treatment plans and reduce adverse events. Lastly, embracing innovation and collaboration can improve the standard of care in chronic pain management by striking a balance between pain relief and patient safety
publishDate 2024
dc.date.none.fl_str_mv 2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/11000/32545
url https://hdl.handle.net/11000/32545
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.3390/ijms25115925
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv application/pdf
32
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:REDIUMH. Depósito Digital de la UMH
instname:Universidad Miguel Hernández de Elche
instname_str Universidad Miguel Hernández de Elche
reponame_str REDIUMH. Depósito Digital de la UMH
collection REDIUMH. Depósito Digital de la UMH
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869407607478812672
score 15,812429

Registos relacionados