Reelin Signaling by the Prime Neurogenic Niche of the Adult Brain

[Background] During development, reelin sets the pace of neocortical neurogenesis, enabling newborn neurons to migrate. However, whether—and, if so, how—reelin signaling affects the adult neurogenic niches remains uncertain.

Detalhes bibliográficos
Autores: Pérez-Martínez, F. Javier, Cifuentes, Manuel, Luque, Juan M.
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2025
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/413406
Acesso em linha:http://hdl.handle.net/10261/413406
https://api.elsevier.com/content/abstract/scopus_id/105025882089
Access Level:Acceso aberto
Palavra-chave:Adult neurogenesis
ApoER2
Dab1
Ependymal/subependymal zone
Reelin
Rostral migratory stream
Descrição
Resumo:[Background] During development, reelin sets the pace of neocortical neurogenesis, enabling newborn neurons to migrate. However, whether—and, if so, how—reelin signaling affects the adult neurogenic niches remains uncertain.