Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.

Wine E; Aloi M; Van Biervliet S; Bronsky J; di Carpi JM; Gasparetto M; Gianolio L; Gordon H; Hojsak I; Hudson AS; Hussey S; van Limbergen J; Miele E; Norsa L; Olén O; Pellino G; van Rheenen P; de Ridder L; Russell RK; Shouval DS; Trindade E; Turner D; Wilson DC; Yerushalmy Feler A; Assa A

Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.

OBJECTIVES: Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and pr...

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Autores:	Wine E, Aloi M, Van Biervliet S, Bronsky J, di Carpi JM, Gasparetto M, Gianolio L, Gordon H, Hojsak I, Hudson AS, Hussey S, van Limbergen J, Miele E, Norsa L, Olén O, Pellino G, van Rheenen P, de Ridder L, Russell RK, Shouval DS, Trindade E, Turner D, Wilson DC, Yerushalmy Feler A, Assa A
Tipo de recurso:	artículo
Estado:	Versión publicada
Fecha de publicación:	2025
País:	España
Institución:	Fundació Sant Joan de Déu
Repositorio:	r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:	oai:fsjd.fundanetsuite.com:p28947
Acceso en línea:	https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28947
Access Level:	acceso abierto
Palabra clave:	Paediatric Ulcerative Colitis Activity Index biologics children inflammatory bowel disease-unclassified thiopurines

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spelling	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.Wine EAloi MVan Biervliet SBronsky Jdi Carpi JMGasparetto MGianolio LGordon HHojsak IHudson ASHussey Svan Limbergen JMiele ENorsa LOlén OPellino Gvan Rheenen Pde Ridder LRussell RKShouval DSTrindade ETurner DWilson DCYerushalmy Feler AAssa APaediatric Ulcerative Colitis Activity Indexbiologicschildreninflammatory bowel disease-unclassifiedthiopurinesOBJECTIVES: Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. METHODS: These guidelines are an update to those published in 2018 and are a joint effort of the Paediatric IBD Porto group of European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation. An extensive literature search with subsequent evidence appraisal using the Oxford methodology was performed, followed by three online voting sessions and a consensus face-to-face meeting. Thirty-nine recommendations and 77 practice points were endorsed by the 25 experts with at least an 84% consensus rate. RESULTS: Robust evidence-based recommendations and detailed practice points are provided. In addition to reemphasising and updating the role of more 'traditional' UC therapies, these guidelines outline optimising the use of antitumour necrosis factor therapies and integrating newer biologics and small molecules, as well as supportive therapy, to improve outcomes and provide an updated management algorithm. Measurement and monitoring tools and decision aids are provided, and additional aspects, including nutritional support, extraintestinal manifestations, pouchitis, inflammatory bowel disease-unclassified and patient support, are discussed. Some aspects, including surgery and thromboprophylaxis, are covered in the acute severe UC guidelines. CONCLUSIONS: These guidelines serve as an aid in managing children with UC through a combination of evidence-based recommendations and more practical practice points in the ambulatory setting.WILEY2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28947JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITIONISSN: 02772116ISSNe: 15364801reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p289472026-05-27T12:37:41Z
dc.title.none.fl_str_mv	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.
title	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.
spellingShingle	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation. Wine E Paediatric Ulcerative Colitis Activity Index biologics children inflammatory bowel disease-unclassified thiopurines
title_short	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.
title_full	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.
title_fullStr	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.
title_full_unstemmed	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.
title_sort	Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.
dc.creator.none.fl_str_mv	Wine E Aloi M Van Biervliet S Bronsky J di Carpi JM Gasparetto M Gianolio L Gordon H Hojsak I Hudson AS Hussey S van Limbergen J Miele E Norsa L Olén O Pellino G van Rheenen P de Ridder L Russell RK Shouval DS Trindade E Turner D Wilson DC Yerushalmy Feler A Assa A
author	Wine E
author_facet	Wine E Aloi M Van Biervliet S Bronsky J di Carpi JM Gasparetto M Gianolio L Gordon H Hojsak I Hudson AS Hussey S van Limbergen J Miele E Norsa L Olén O Pellino G van Rheenen P de Ridder L Russell RK Shouval DS Trindade E Turner D Wilson DC Yerushalmy Feler A Assa A
author_role	author
author2	Aloi M Van Biervliet S Bronsky J di Carpi JM Gasparetto M Gianolio L Gordon H Hojsak I Hudson AS Hussey S van Limbergen J Miele E Norsa L Olén O Pellino G van Rheenen P de Ridder L Russell RK Shouval DS Trindade E Turner D Wilson DC Yerushalmy Feler A Assa A
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author
dc.subject.none.fl_str_mv	Paediatric Ulcerative Colitis Activity Index biologics children inflammatory bowel disease-unclassified thiopurines
topic	Paediatric Ulcerative Colitis Activity Index biologics children inflammatory bowel disease-unclassified thiopurines
description	OBJECTIVES: Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. METHODS: These guidelines are an update to those published in 2018 and are a joint effort of the Paediatric IBD Porto group of European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation. An extensive literature search with subsequent evidence appraisal using the Oxford methodology was performed, followed by three online voting sessions and a consensus face-to-face meeting. Thirty-nine recommendations and 77 practice points were endorsed by the 25 experts with at least an 84% consensus rate. RESULTS: Robust evidence-based recommendations and detailed practice points are provided. In addition to reemphasising and updating the role of more 'traditional' UC therapies, these guidelines outline optimising the use of antitumour necrosis factor therapies and integrating newer biologics and small molecules, as well as supportive therapy, to improve outcomes and provide an updated management algorithm. Measurement and monitoring tools and decision aids are provided, and additional aspects, including nutritional support, extraintestinal manifestations, pouchitis, inflammatory bowel disease-unclassified and patient support, are discussed. Some aspects, including surgery and thromboprophylaxis, are covered in the acute severe UC guidelines. CONCLUSIONS: These guidelines serve as an aid in managing children with UC through a combination of evidence-based recommendations and more practical practice points in the ambulatory setting.
publishDate	2025
dc.date.none.fl_str_mv	2025
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28947
url	https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28947
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	WILEY
publisher.none.fl_str_mv	WILEY
dc.source.none.fl_str_mv	JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION ISSN: 02772116 ISSNe: 15364801 reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname:Fundació Sant Joan de Déu
instname_str	Fundació Sant Joan de Déu
reponame_str	r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection	r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
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Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation.

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