Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people

Background: Impairment of social cognition is documented in bipolar disorder (BD) and schizophrenia/schizoaffective disorder (SCH). In healthy individuals, women perform better than men in some of its sub-domains. However, in BD and SCH the results are mixed. Our aim was to compare emotion recogniti...

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Autores: Navarra-Ventura, G, Vicent-Gil, M, Serra-Blasco, M, Massons, C, Crosas, JM, Cobo, J, Jubert, A, Jodar, M, Fernandez-Gonzalo, S, Goldberg, X, Palao, D, Lahera, G, Vieta, E, Cardoner, N
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Recursos:Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repositorio:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:oai:i3pt.fundanetsuite.com:p1987
Acesso em linha:https://i3pt.portalinvestigacion.com/publicaciones/1987
Access Level:acceso abierto
Palavra-chave:Sex differences
Emotion recognition
Theory of mind
Bipolar disorder
Schizophrenia
Healthy people
Subthreshold depression
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spelling Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy peopleNavarra-Ventura, GVicent-Gil, MSerra-Blasco, MMassons, CCrosas, JMCobo, JJubert, AJodar, MFernandez-Gonzalo, SGoldberg, XPalao, DLahera, GVieta, ECardoner, NSex differencesEmotion recognitionTheory of mindBipolar disorderSchizophreniaHealthy peopleSubthreshold depressionBackground: Impairment of social cognition is documented in bipolar disorder (BD) and schizophrenia/schizoaffective disorder (SCH). In healthy individuals, women perform better than men in some of its sub-domains. However, in BD and SCH the results are mixed. Our aim was to compare emotion recognition, affective Theory of Mind (ToM) and first- and second-order cognitive ToM in BD, SCH and healthy subjects, and to investigate sex-related differences. Methods: 120 patients (BD = 60, SCH = 60) and 40 healthy subjects were recruited. Emotion recognition was assessed by the Pictures of Facial Affect (POFA) test, affective ToM by the Reading the Mind in the Eyes Test (RMET) and cognitive ToM by several false-belief stories. Group and sex differences were analyzed using parametric (POFA, RMET) and non-parametric (false-belief stories) tests. The impact of age, intelligence quotient (IQ) and clinical variables on patient performance was examined using a series of linear/logistic regressions. Results: Both groups of patients performed worse than healthy subjects on POFA, RMET and second-order falsebelief (p < 0.001), but no differences were found between them. Instead, their deficits were related to older age and/or lower IQ (p < 0.01). Subthreshold depression was associated with a 6-fold increased risk of first-order false-belief failure (p < 0.001). Sex differences were only found in healthy subjects, with women outperforming men on POFA and RMET (p <= 0.012), but not on first/second-order false-belief. Limitations: The cross-sectional design does not allow for causal inferences. Conclusion: BD and SCH patients had deficits in emotion recognition, affective ToM, and second-order cognitive ToM, but their performance was comparable to each other, highlighting that the differences between them may be subtler than previously thought. First-order cognitive ToM remained intact, but subthreshold depression altered their normal functioning. Our results suggest that the advantage of healthy women in the emotional and affective aspects of social cognition would not be maintained in BD and SCH.W B SAUNDERS CO-ELSEVIER INC2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://i3pt.portalinvestigacion.com/publicaciones/1987COMPREHENSIVE PSYCHIATRYISSN: 0010440XISSNe: 15328384reponame:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulíinstname:Institut d'Investigació i Innovació Parc Taulí (I3PT)Inglésinfo:eu-repo/semantics/openAccessoai:i3pt.fundanetsuite.com:p19872026-06-21T15:30:37Z
dc.title.none.fl_str_mv Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
title Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
spellingShingle Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
Navarra-Ventura, G
Sex differences
Emotion recognition
Theory of mind
Bipolar disorder
Schizophrenia
Healthy people
Subthreshold depression
title_short Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
title_full Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
title_fullStr Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
title_full_unstemmed Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
title_sort Group and sex differences in social cognition in bipolar disorder, schizophrenia/schizoaffective disorder and healthy people
dc.creator.none.fl_str_mv Navarra-Ventura, G
Vicent-Gil, M
Serra-Blasco, M
Massons, C
Crosas, JM
Cobo, J
Jubert, A
Jodar, M
Fernandez-Gonzalo, S
Goldberg, X
Palao, D
Lahera, G
Vieta, E
Cardoner, N
author Navarra-Ventura, G
author_facet Navarra-Ventura, G
Vicent-Gil, M
Serra-Blasco, M
Massons, C
Crosas, JM
Cobo, J
Jubert, A
Jodar, M
Fernandez-Gonzalo, S
Goldberg, X
Palao, D
Lahera, G
Vieta, E
Cardoner, N
author_role author
author2 Vicent-Gil, M
Serra-Blasco, M
Massons, C
Crosas, JM
Cobo, J
Jubert, A
Jodar, M
Fernandez-Gonzalo, S
Goldberg, X
Palao, D
Lahera, G
Vieta, E
Cardoner, N
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Sex differences
Emotion recognition
Theory of mind
Bipolar disorder
Schizophrenia
Healthy people
Subthreshold depression
topic Sex differences
Emotion recognition
Theory of mind
Bipolar disorder
Schizophrenia
Healthy people
Subthreshold depression
description Background: Impairment of social cognition is documented in bipolar disorder (BD) and schizophrenia/schizoaffective disorder (SCH). In healthy individuals, women perform better than men in some of its sub-domains. However, in BD and SCH the results are mixed. Our aim was to compare emotion recognition, affective Theory of Mind (ToM) and first- and second-order cognitive ToM in BD, SCH and healthy subjects, and to investigate sex-related differences. Methods: 120 patients (BD = 60, SCH = 60) and 40 healthy subjects were recruited. Emotion recognition was assessed by the Pictures of Facial Affect (POFA) test, affective ToM by the Reading the Mind in the Eyes Test (RMET) and cognitive ToM by several false-belief stories. Group and sex differences were analyzed using parametric (POFA, RMET) and non-parametric (false-belief stories) tests. The impact of age, intelligence quotient (IQ) and clinical variables on patient performance was examined using a series of linear/logistic regressions. Results: Both groups of patients performed worse than healthy subjects on POFA, RMET and second-order falsebelief (p < 0.001), but no differences were found between them. Instead, their deficits were related to older age and/or lower IQ (p < 0.01). Subthreshold depression was associated with a 6-fold increased risk of first-order false-belief failure (p < 0.001). Sex differences were only found in healthy subjects, with women outperforming men on POFA and RMET (p <= 0.012), but not on first/second-order false-belief. Limitations: The cross-sectional design does not allow for causal inferences. Conclusion: BD and SCH patients had deficits in emotion recognition, affective ToM, and second-order cognitive ToM, but their performance was comparable to each other, highlighting that the differences between them may be subtler than previously thought. First-order cognitive ToM remained intact, but subthreshold depression altered their normal functioning. Our results suggest that the advantage of healthy women in the emotional and affective aspects of social cognition would not be maintained in BD and SCH.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://i3pt.portalinvestigacion.com/publicaciones/1987
url https://i3pt.portalinvestigacion.com/publicaciones/1987
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv W B SAUNDERS CO-ELSEVIER INC
publisher.none.fl_str_mv W B SAUNDERS CO-ELSEVIER INC
dc.source.none.fl_str_mv COMPREHENSIVE PSYCHIATRY
ISSN: 0010440X
ISSNe: 15328384
reponame:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
instname:Institut d'Investigació i Innovació Parc Taulí (I3PT)
instname_str Institut d'Investigació i Innovació Parc Taulí (I3PT)
reponame_str r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
collection r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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