Mitochondrial toxins and neurodegenerative diseases

The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in respiratory chain complex activities in mitochondria seems to be a causative factor. The aim of this review is to describe the most important toxins affecting the mitochondrial funct...

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Detalles Bibliográficos
Autores: Ayala Gómez, Antonio, Venero Recio, José Luis, Cano, Josefina, Machado, Alberto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/130858
Acceso en línea:https://hdl.handle.net/11441/130858
https://doi.org/10.2741/2119
Access Level:acceso abierto
Palabra clave:Parkinson´s Disease
Huntington´s disease
Rotenone
3-NPA
Isoquinolines
Review
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spelling Mitochondrial toxins and neurodegenerative diseasesAyala Gómez, AntonioVenero Recio, José LuisCano, JosefinaMachado, AlbertoParkinson´s DiseaseHuntington´s diseaseRotenone3-NPAIsoquinolinesReviewThe selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in respiratory chain complex activities in mitochondria seems to be a causative factor. The aim of this review is to describe the most important toxins affecting the mitochondrial function, which could be involved in the incidence of some of these diseases: MPTP, rotenone and 3-nitropropionic (3-NPA).IMR PressBioquímica y Biología Molecular2007info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/130858https://doi.org/10.2741/2119reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésFrontiers in Bioscience-Landmark, 12 (3), 986-1007.https://doi.org/10.2741/2119info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1308582026-06-17T12:51:07Z
dc.title.none.fl_str_mv Mitochondrial toxins and neurodegenerative diseases
title Mitochondrial toxins and neurodegenerative diseases
spellingShingle Mitochondrial toxins and neurodegenerative diseases
Ayala Gómez, Antonio
Parkinson´s Disease
Huntington´s disease
Rotenone
3-NPA
Isoquinolines
Review
title_short Mitochondrial toxins and neurodegenerative diseases
title_full Mitochondrial toxins and neurodegenerative diseases
title_fullStr Mitochondrial toxins and neurodegenerative diseases
title_full_unstemmed Mitochondrial toxins and neurodegenerative diseases
title_sort Mitochondrial toxins and neurodegenerative diseases
dc.creator.none.fl_str_mv Ayala Gómez, Antonio
Venero Recio, José Luis
Cano, Josefina
Machado, Alberto
author Ayala Gómez, Antonio
author_facet Ayala Gómez, Antonio
Venero Recio, José Luis
Cano, Josefina
Machado, Alberto
author_role author
author2 Venero Recio, José Luis
Cano, Josefina
Machado, Alberto
author2_role author
author
author
dc.contributor.none.fl_str_mv Bioquímica y Biología Molecular
dc.subject.none.fl_str_mv Parkinson´s Disease
Huntington´s disease
Rotenone
3-NPA
Isoquinolines
Review
topic Parkinson´s Disease
Huntington´s disease
Rotenone
3-NPA
Isoquinolines
Review
description The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in respiratory chain complex activities in mitochondria seems to be a causative factor. The aim of this review is to describe the most important toxins affecting the mitochondrial function, which could be involved in the incidence of some of these diseases: MPTP, rotenone and 3-nitropropionic (3-NPA).
publishDate 2007
dc.date.none.fl_str_mv 2007
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/130858
https://doi.org/10.2741/2119
url https://hdl.handle.net/11441/130858
https://doi.org/10.2741/2119
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Frontiers in Bioscience-Landmark, 12 (3), 986-1007.
https://doi.org/10.2741/2119
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv IMR Press
publisher.none.fl_str_mv IMR Press
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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