Replication Data for: Metabolic profiling of (poly)phenolic compounds in mouse urine following consumption of hull-less and purple-grain barley

This study aimed to explore the metabolic fate of (poly)phenolic compounds in a unique anthocyanin-rich purple barley. Using Balb/c mice, researchers analyzed urine samples after a six-week diet of either standard food or whole-grain barley. They identified 39 (poly)phenolic compounds in the barley...

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Detalhes bibliográficos
Autores: Rubió Piqué, Laura, Cortijo-Alfonso, Maria Engracia, Yuste, Silvia, Friero, Ivan, Martínez Subirà, Mariona, Moralejo Vidal, Mª Angeles, Piñol Felis, Carme, Macià i Puig, Ma Alba
Formato: conjunto de datos
Fecha de publicación:2024
País:España
Recursos:Consorci de Serveis Universitaris de Catalunya (CSUC)
Repositorio:CORA.Repositori de Dades de Recerca
OAI Identifier:oai:dnet:cora.rdr____::937f5a374345bbe944446d0e20ce15c2
Acesso em linha:https://doi.org/10.34810/DATA1387
Access Level:acceso abierto
Palavra-chave:Medicine, Health and Life Sciences
anthocyanins
UPLC-MS/MS
barley
bioavailability
polyphenols
Liquid Chromatography-Mass Spectrometry
Descrição
Resumo:This study aimed to explore the metabolic fate of (poly)phenolic compounds in a unique anthocyanin-rich purple barley. Using Balb/c mice, researchers analyzed urine samples after a six-week diet of either standard food or whole-grain barley. They identified 39 (poly)phenolic compounds in the barley and 42 metabolites in urine post-consumption, including unique phase-II conjugates and colonic catabolites. The findings offer insights into the metabolism of these compounds in purple barley, paving the way for future research on its potential health benefits. The dataset includes an experimental summary of the (poly)phenolic profile of a hull-less, purple barley genotype biofortified with anthocyanins, compared to a standard diet. It also covers the (poly)phenolic metabolites identified in urine samples from mice after sustained intake. The barley's (poly)phenolic compounds are categorized into free and bound fractions, including anthocyanins, phenolic acids, flavan-3-ols, and flavones. The metabolites in mice urine predominantly consist of phase-II sulphated, glucuronided, and methylated conjugates, along with colonic catabolites.