Venlafaxine-PLGA nanoparticles provide a fast onset of action in an animal model of depression via nose-to-brain

[Background] Current treatment of depression is hindered by the delayed onset of the action of antidepressant drugs, often resulting in treatment failure. Therefore, new therapeutic solutions are imperative.

Detalhes bibliográficos
Autores: Cayero Otero, María Dolores, Pérez Caballero, Laura, Suárez-Pereira, Irene, Hidalgo Figueroa, María, Delgado Sequera, Alejandra, Montesinos, Juan Manuel, Berrocoso, Esther, Martín-Banderas, Lucía
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2025
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/391052
Acesso em linha:http://hdl.handle.net/10261/391052
https://api.elsevier.com/content/abstract/scopus_id/105004893526
Access Level:Acceso aberto
Palavra-chave:Depression
Nose-to-brain
PLGA nanoparticles
Venlafaxine
Descrição
Resumo:[Background] Current treatment of depression is hindered by the delayed onset of the action of antidepressant drugs, often resulting in treatment failure. Therefore, new therapeutic solutions are imperative.

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