Personalized nanomedicine: a revolution at the nanoscale

Nanomedicine is an interdisciplinary research field that results from the application of nanotechnology to medicine and has the potential to significantly improve some current treatments. Specifically, in the field of personalized medicine, it is expected to have a great impact in the near future du...

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Detalles Bibliográficos
Autores: Fornaguera, Cristina, García Celma, Ma José
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/157641
Acceso en línea:https://hdl.handle.net/2445/157641
Access Level:acceso abierto
Palabra clave:Nanomedicina
Nanotecnologia
Assistència mèdica
Indústria farmacèutica
Nanomedicine
Nanotechnology
Medical care
Pharmaceutical industry
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spelling Personalized nanomedicine: a revolution at the nanoscaleFornaguera, CristinaGarcía Celma, Ma JoséNanomedicinaNanotecnologiaAssistència mèdicaIndústria farmacèuticaNanomedicineNanotechnologyMedical carePharmaceutical industryNanomedicine is an interdisciplinary research field that results from the application of nanotechnology to medicine and has the potential to significantly improve some current treatments. Specifically, in the field of personalized medicine, it is expected to have a great impact in the near future due to its multiple advantages, namely its versatility to adapt a drug to a cohort of patients. In the present review, the properties and requirements of pharmaceutical dosage forms at the nanoscale, so-called nanomedicines, are been highlighted. An overview of the main current nanomedicines in pre-clinical and clinical development is presented, detailing the challenges to the personalization of these therapies. Next, the process of development of novel nanomedicines is described, from their design in research labs to their arrival on the market, including considerations for the design of nanomedicines adapted to the requirements of the market to achieve safe, effective, and quality products. Finally, attention is given to the point of view of the pharmaceutical industry, including regulation issues applied to the specific case of personalized medicine. The authors expect this review to be a useful overview of the current state of the art of nanomedicine research and industrial production, and the future opportunities of personalized medicine in the upcoming years. The authors encourage the development and marketing of novel personalized nanomedicines.MDPI2020202020172020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion20 p.application/pdfhttps://hdl.handle.net/2445/157641Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.3390/jpm7040012Journal of Personalized Medicine, 2017, vol. 7, num. 4, p. 12https://doi.org/10.3390/jpm7040012cc-by (c) Fornaguera, Cristina et al., 2017http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/1576412026-05-29T05:05:01Z
dc.title.none.fl_str_mv Personalized nanomedicine: a revolution at the nanoscale
title Personalized nanomedicine: a revolution at the nanoscale
spellingShingle Personalized nanomedicine: a revolution at the nanoscale
Fornaguera, Cristina
Nanomedicina
Nanotecnologia
Assistència mèdica
Indústria farmacèutica
Nanomedicine
Nanotechnology
Medical care
Pharmaceutical industry
title_short Personalized nanomedicine: a revolution at the nanoscale
title_full Personalized nanomedicine: a revolution at the nanoscale
title_fullStr Personalized nanomedicine: a revolution at the nanoscale
title_full_unstemmed Personalized nanomedicine: a revolution at the nanoscale
title_sort Personalized nanomedicine: a revolution at the nanoscale
dc.creator.none.fl_str_mv Fornaguera, Cristina
García Celma, Ma José
author Fornaguera, Cristina
author_facet Fornaguera, Cristina
García Celma, Ma José
author_role author
author2 García Celma, Ma José
author2_role author
dc.subject.none.fl_str_mv Nanomedicina
Nanotecnologia
Assistència mèdica
Indústria farmacèutica
Nanomedicine
Nanotechnology
Medical care
Pharmaceutical industry
topic Nanomedicina
Nanotecnologia
Assistència mèdica
Indústria farmacèutica
Nanomedicine
Nanotechnology
Medical care
Pharmaceutical industry
description Nanomedicine is an interdisciplinary research field that results from the application of nanotechnology to medicine and has the potential to significantly improve some current treatments. Specifically, in the field of personalized medicine, it is expected to have a great impact in the near future due to its multiple advantages, namely its versatility to adapt a drug to a cohort of patients. In the present review, the properties and requirements of pharmaceutical dosage forms at the nanoscale, so-called nanomedicines, are been highlighted. An overview of the main current nanomedicines in pre-clinical and clinical development is presented, detailing the challenges to the personalization of these therapies. Next, the process of development of novel nanomedicines is described, from their design in research labs to their arrival on the market, including considerations for the design of nanomedicines adapted to the requirements of the market to achieve safe, effective, and quality products. Finally, attention is given to the point of view of the pharmaceutical industry, including regulation issues applied to the specific case of personalized medicine. The authors expect this review to be a useful overview of the current state of the art of nanomedicine research and industrial production, and the future opportunities of personalized medicine in the upcoming years. The authors encourage the development and marketing of novel personalized nanomedicines.
publishDate 2017
dc.date.none.fl_str_mv 2017
2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/157641
url https://hdl.handle.net/2445/157641
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/jpm7040012
Journal of Personalized Medicine, 2017, vol. 7, num. 4, p. 12
https://doi.org/10.3390/jpm7040012
dc.rights.none.fl_str_mv cc-by (c) Fornaguera, Cristina et al., 2017
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Fornaguera, Cristina et al., 2017
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 20 p.
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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