Chapter One – Larock Reaction in the synthesis of heterocyclic compounds

The indole ring is one of the most common features in natural products and small molecules with important bioactivity. Larock reported a new methodology for the synthesis of the indole ring system based on the palladium-catalyzed heteroannulation of 2-iodoaniline and substituted alkyne moieties. Thi...

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Detalles Bibliográficos
Autores: Herraiz Cobo, Jesús, Albericio Palomera, Fernando, Álvarez Domingo, Mercedes
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2015
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/65732
Acceso en línea:https://hdl.handle.net/2445/65732
Access Level:acceso abierto
Palabra clave:Química orgànica
Síntesi orgànica
Compostos heterocíclics
Organic chemistry
Organic synthesis
Heterocyclic compounds
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spelling Chapter One – Larock Reaction in the synthesis of heterocyclic compoundsHerraiz Cobo, JesúsAlbericio Palomera, FernandoÁlvarez Domingo, MercedesQuímica orgànicaSíntesi orgànicaCompostos heterocíclicsOrganic chemistryOrganic synthesisHeterocyclic compoundsThe indole ring is one of the most common features in natural products and small molecules with important bioactivity. Larock reported a new methodology for the synthesis of the indole ring system based on the palladium-catalyzed heteroannulation of 2-iodoaniline and substituted alkyne moieties. This procedure was subsequently extended to the preparation of other nitrogen- and oxygen- containing heterocycles. This is the process of choice for the synthesis of a large number of heterocyclic derivatives, as it provides outstanding regioselectivity and good to excellent yields.Elsevier2015201520152015info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion46 p.application/pdfhttps://hdl.handle.net/2445/65732Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: http://dx.doi.org/10.1016/bs.aihch.2015.04.003Advances in Heterocyclic Chemistry, 2015, vol. 116, p. 1-35http://dx.doi.org/10.1016/bs.aihch.2015.04.003(c) Elsevier, 2015info:eu-repo/semantics/openAccessoai:recercat.cat:2445/657322026-05-29T05:05:01Z
dc.title.none.fl_str_mv Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
title Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
spellingShingle Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
Herraiz Cobo, Jesús
Química orgànica
Síntesi orgànica
Compostos heterocíclics
Organic chemistry
Organic synthesis
Heterocyclic compounds
title_short Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
title_full Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
title_fullStr Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
title_full_unstemmed Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
title_sort Chapter One – Larock Reaction in the synthesis of heterocyclic compounds
dc.creator.none.fl_str_mv Herraiz Cobo, Jesús
Albericio Palomera, Fernando
Álvarez Domingo, Mercedes
author Herraiz Cobo, Jesús
author_facet Herraiz Cobo, Jesús
Albericio Palomera, Fernando
Álvarez Domingo, Mercedes
author_role author
author2 Albericio Palomera, Fernando
Álvarez Domingo, Mercedes
author2_role author
author
dc.subject.none.fl_str_mv Química orgànica
Síntesi orgànica
Compostos heterocíclics
Organic chemistry
Organic synthesis
Heterocyclic compounds
topic Química orgànica
Síntesi orgànica
Compostos heterocíclics
Organic chemistry
Organic synthesis
Heterocyclic compounds
description The indole ring is one of the most common features in natural products and small molecules with important bioactivity. Larock reported a new methodology for the synthesis of the indole ring system based on the palladium-catalyzed heteroannulation of 2-iodoaniline and substituted alkyne moieties. This procedure was subsequently extended to the preparation of other nitrogen- and oxygen- containing heterocycles. This is the process of choice for the synthesis of a large number of heterocyclic derivatives, as it provides outstanding regioselectivity and good to excellent yields.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015
2015
2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/65732
url https://hdl.handle.net/2445/65732
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: http://dx.doi.org/10.1016/bs.aihch.2015.04.003
Advances in Heterocyclic Chemistry, 2015, vol. 116, p. 1-35
http://dx.doi.org/10.1016/bs.aihch.2015.04.003
dc.rights.none.fl_str_mv (c) Elsevier, 2015
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Elsevier, 2015
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 46 p.
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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