Nanocarriers for enhancing the performance of immunomodulatory molecules

Nanotechnology offers the possibility of enhancing the performance of immunomodulatory molecules by facilitating their transport across biological barriers and targeting them to the immune system. Considering this promising potential, this thesis has focused on the development of polymeric nanocarri...

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Detalles Bibliográficos
Autor: Olivera Fernández, Ana
Tipo de recurso: tesis doctoral
Fecha de publicación:2020
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/24343
Acceso en línea:http://hdl.handle.net/10347/24343
Access Level:acceso abierto
Palabra clave:Materias::Investigación::32 Ciencias médicas::3209 Farmacología::320908 Preparación de medicamentos
Materias::Investigación::32 Ciencias médicas::3207 Patología::320710 Inmunopatología
Materias::Investigación::32 Ciencias médicas::3209 Farmacología::320903 Evaluación de medicamentos
Descripción
Sumario:Nanotechnology offers the possibility of enhancing the performance of immunomodulatory molecules by facilitating their transport across biological barriers and targeting them to the immune system. Considering this promising potential, this thesis has focused on the development of polymeric nanocarriers loaded with an immunomodulatory molecule for the prevention of type 1 diabetes. Furthermore, pursuing the transdermal supplementation of this molecule, these nanocarriers were optimized to enhance its penetration across the skin.