Enantiospecific Synthesis of 1,3-Disubstituted Allenes from Propargylic Carbonates through a Borylation-1,2-Elimination Process
An array of enantioenriched vinyl boronates bearing an allylic carbonate moiety have been prepared through selective hydroboration of propargyl carbonates. Treatment of these vinyl boronates with TBAF in THF affords enantioenriched 1,3-disubstituted allenes through a novel 1,2-anti elimination in go...
| Autores: | , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/395544 |
| Acceso en línea: | http://hdl.handle.net/10261/395544 https://api.elsevier.com/content/abstract/scopus_id/85177649840 |
| Access Level: | acceso abierto |
| Palabra clave: | 1,2-anti-elimination Allenes Boronates Propargylic carbonates TBAF |
| Sumario: | An array of enantioenriched vinyl boronates bearing an allylic carbonate moiety have been prepared through selective hydroboration of propargyl carbonates. Treatment of these vinyl boronates with TBAF in THF affords enantioenriched 1,3-disubstituted allenes through a novel 1,2-anti elimination in good yields and high enantiospecificities. |
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