On the Analysis of Speech and Disfluencies for Automatic Detection of Mild Cognitive Impairment

Alzheimer's disease is characterized by a progressive and irreversible cognitive deterioration. In a previous stage, the so-called Mild Cognitive Impairment or cognitive loss appears. Nevertheless, this previous stage does not seem sufficiently severe to interfere in independent abilities of da...

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Detalles Bibliográficos
Autores: López de Ipiña Peña, Miren Karmele, Martínez de Lizarduy Sturtze, Unai, Calvo Salomón, Pilar María, Beitia Bengoa, Blanca, García Melero, Joseba, Fernández Gómez de Segura, Elsa, Ecay Torres, Miriam, Faúndez Zanuy, Marcos, Sanz, P.
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/50209
Acceso en línea:http://hdl.handle.net/10810/50209
Access Level:acceso abierto
Palabra clave:mild cognitive impairment
automatic speech analysis
deep learning
convolutional neural networks
nonlinear features
disfluencies
alzheimers
disease
Descripción
Sumario:Alzheimer's disease is characterized by a progressive and irreversible cognitive deterioration. In a previous stage, the so-called Mild Cognitive Impairment or cognitive loss appears. Nevertheless, this previous stage does not seem sufficiently severe to interfere in independent abilities of daily life, so it is usually diagnosed inappropriately. Thus, its detection is a crucial challenge to be addressed by medical specialists. This paper presents a novel proposal for such early diagnosis based on automatic analysis of speech and disfluencies, and Deep Learning methodologies. The proposed tools could be useful for supporting Mild Cognitive Impairment diagnosis. The Deep Learning approach includes Convolutional Neural Networks and nonlinear multifeature modeling. Additionally, an automatic hybrid methodology is used in order to select the most relevant features by means of nonparametric Mann-Whitney U test and Support Vector Machine Attribute evaluation.