Redefining biomaterial biocompatibility: challenges for artificial intelligence and text mining

The surge in ‘Big data’ has significantly influenced biomaterials research and development, with vast data volumes emerging from clinical trials, scientific literature, electronic health records, and other sources. Biocompatibility is essential in developing safe medical devices and biomaterials to...

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Detalles Bibliográficos
Autores: Mateu Sanz, Miguel|||0000-0001-5117-6071, Fuenteslópez, Carla V., Uribe Gomez, Juan, Haugen, Håvard Jostein, Pandit, Abhay, Ginebra Molins, Maria Pau|||0000-0002-4700-5621, Hakimi, Osnat|||0000-0002-8839-4846, Krallinger, Martin, Samara, Athina
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/396601
Acceso en línea:https://hdl.handle.net/2117/396601
https://dx.doi.org/10.1016/j.tibtech.2023.09.015
Access Level:acceso abierto
Palabra clave:Biomedical materials
Databases
Artificial intelligence
Data mining
Natural language processing (Computer science)
Standardization
Biomaterial
Biocompatibility
Natural language processing
International organization for standardization (ISO)
Materials biomèdics
Bases de dades
Intel·ligència artificial
Mineria de dades
Tractament del llenguatge natural (Informàtica)
Normalització
Àrees temàtiques de la UPC::Enginyeria dels materials
Descripción
Sumario:The surge in ‘Big data’ has significantly influenced biomaterials research and development, with vast data volumes emerging from clinical trials, scientific literature, electronic health records, and other sources. Biocompatibility is essential in developing safe medical devices and biomaterials to perform as intended without provoking adverse reactions. Therefore, establishing an artificial intelligence (AI)-driven biocompatibility definition has become decisive for automating data extraction and profiling safety effectiveness. This definition should both reflect the attributes related to biocompatibility and be compatible with computational data-mining methods. Here, we discuss the need for a comprehensive and contemporary definition of biocompatibility and the challenges in developing one. We also identify the key elements that comprise biocompatibility, and propose an integrated biocompatibility definition that enables data-mining approaches.