The effects of inversions on mitotic recombination in Drosophila melanogaster

The effect of inversions on mitotic recombination outside the inversion was studied in inversion-heterozygotes. Seven euchromatic inversions of the X-chromosome, with breakpoints within the interval between two cell markers, were chosen. The size of the inverted region and the distance from the prox...

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Detalles Bibliográficos
Autores: García-Bellido, Antonio, Wandosell, Francisco
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1978
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/407422
Acceso en línea:http://hdl.handle.net/10261/407422
Access Level:acceso abierto
Palabra clave:Recombination
Somatic Cell
Homologous Sequence
Cell Marker
Interphase Nucleus
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spelling The effects of inversions on mitotic recombination in Drosophila melanogasterGarcía-Bellido, AntonioWandosell, FranciscoRecombinationSomatic CellHomologous SequenceCell MarkerInterphase NucleusThe effect of inversions on mitotic recombination outside the inversion was studied in inversion-heterozygotes. Seven euchromatic inversions of the X-chromosome, with breakpoints within the interval between two cell markers, were chosen. The size of the inverted region and the distance from the proximal breakpoint to the proximal cell marker varied. Mitotic recombination was X-ray induced in larvae and clones scored in the tergites of emerged adults. The frequency of recombinants between both cell markers and the frequency of recombinants proximal to the proximal cell marker was used to estimate the effect of interference in pairing caused by the inversions. Such an effect only occurs in small chromosome intervals. This indicates that homologous sequences are tightly paired in the interphase nuclei of somatic cells. This conclusion is derived from data based on X-ray induced mitotic recombination. The possibility of extending this conclusion to non-irradiated cells is discussed.Peer reviewedSpringerConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202520251978info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/407422reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1007/BF00331007Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4074222026-05-22T06:33:51Z
dc.title.none.fl_str_mv The effects of inversions on mitotic recombination in Drosophila melanogaster
title The effects of inversions on mitotic recombination in Drosophila melanogaster
spellingShingle The effects of inversions on mitotic recombination in Drosophila melanogaster
García-Bellido, Antonio
Recombination
Somatic Cell
Homologous Sequence
Cell Marker
Interphase Nucleus
title_short The effects of inversions on mitotic recombination in Drosophila melanogaster
title_full The effects of inversions on mitotic recombination in Drosophila melanogaster
title_fullStr The effects of inversions on mitotic recombination in Drosophila melanogaster
title_full_unstemmed The effects of inversions on mitotic recombination in Drosophila melanogaster
title_sort The effects of inversions on mitotic recombination in Drosophila melanogaster
dc.creator.none.fl_str_mv García-Bellido, Antonio
Wandosell, Francisco
author García-Bellido, Antonio
author_facet García-Bellido, Antonio
Wandosell, Francisco
author_role author
author2 Wandosell, Francisco
author2_role author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Recombination
Somatic Cell
Homologous Sequence
Cell Marker
Interphase Nucleus
topic Recombination
Somatic Cell
Homologous Sequence
Cell Marker
Interphase Nucleus
description The effect of inversions on mitotic recombination outside the inversion was studied in inversion-heterozygotes. Seven euchromatic inversions of the X-chromosome, with breakpoints within the interval between two cell markers, were chosen. The size of the inverted region and the distance from the proximal breakpoint to the proximal cell marker varied. Mitotic recombination was X-ray induced in larvae and clones scored in the tergites of emerged adults. The frequency of recombinants between both cell markers and the frequency of recombinants proximal to the proximal cell marker was used to estimate the effect of interference in pairing caused by the inversions. Such an effect only occurs in small chromosome intervals. This indicates that homologous sequences are tightly paired in the interphase nuclei of somatic cells. This conclusion is derived from data based on X-ray induced mitotic recombination. The possibility of extending this conclusion to non-irradiated cells is discussed.
publishDate 1978
dc.date.none.fl_str_mv 1978
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/407422
url http://hdl.handle.net/10261/407422
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1007/BF00331007
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812455

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