First Detection of SARS-CoV-2 Delta (B.1.617.2) Variant of Concern in a Dog with Clinical Signs in Spain

Several cases of naturally infected dogs with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported despite the apparently low susceptibility of this species. Here, we document the first reported case of infection caused by the Delta (B.1.617.2) variant of concern (VOC) in...

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Detalles Bibliográficos
Autores: Fernández-Bastit, Leira|||0000-0002-7766-939X, Rodon, Jordi|||0000-0002-1032-9091, Pradenas, Edwards|||0000-0001-5162-8920, Marfil, Sílvia|||0000-0003-0139-5000, Trinité, Benjamin|||0000-0003-3809-042X, Parera, Mariona|||0000-0002-0756-8307, Roca, Núria, Pou, Anna, Cantero, Guillermo|||0000-0003-4200-503X, Lorca-Oró, Cristina|||0000-0001-5351-4169, Carrillo, Jorge|||0000-0003-0221-5948, Izquierdo Useros, Nuria|||0000-0002-1039-1821, Clotet Sala, Bonaventura|||0000-0003-3232-4598, Noguera-Julian, Marc|||0000-0002-6194-1395, Blanco, Julià|||0000-0002-2225-0217, Vergara-Alert, Júlia|||0000-0001-7484-444X, Segalés Coma, Joaquim|||0000-0002-1539-7261
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:266219
Acceso en línea:https://ddd.uab.cat/record/266219
https://dx.doi.org/urn:doi:10.3390/v13122526
Access Level:acceso abierto
Palabra clave:SARS-CoV-2
B.1.617.2
Delta variant
Variants of concern
COVID-19
Dog
Pets
Transmission
Reverse zoonosis
Descripción
Sumario:Several cases of naturally infected dogs with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported despite the apparently low susceptibility of this species. Here, we document the first reported case of infection caused by the Delta (B.1.617.2) variant of concern (VOC) in a dog in Spain that lived with several household members suffering from Coronavirus Infectious Disease 2019 (COVID-19). The animal displayed mild digestive and respiratory clinical signs and had a low viral load in the oropharyngeal swab collected at the first sampling. Whole-genome sequencing indicated infection with the Delta variant, coinciding with the predominant variant during the fifth pandemic wave in Spain. The dog seroconverted, as detected 21 days after the first sampling, and developed neutralizing antibodies that cross-neutralized different SARS-CoV-2 variants. This study further emphasizes the importance of studying the susceptibility of animal species to different VOCs and their potential role as reservoirs in the context of COVID-19.

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