The Role of Sleep Quality, Trait Anxiety and Hypothalamic-Pituitary-Adrenal Axis Measures in Cognitive Abilities of Healthy Individuals

Sleep plays a crucial role in cognitive processes. Sleep and wake memory consolidation seem to be regulated by glucocorticoids, pointing out the potential role of the hypothalamic-pituitary-adrenal (HPA) axis in the relationship between sleep quality and cognitive abilities. Trait anxiety is another...

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Detalles Bibliográficos
Autores: Labad, Javier|||0000-0003-2214-1886, Urretavizcaya, Mikel|||0000-0002-9746-4068, Monreal Ortiz, Jose Antonio|||0000-0002-0906-927X, Crespo, José Manuel, Vilella, Elisabet|||0000-0002-1887-5919, Palao, Diego|||0000-0002-3323-6568, Menchón Magriñá, José Manuel|||0000-0002-6231-6524, Soria, Virginia|||0000-0001-6412-6831, Salvat-Pujol, Neus|||0000-0001-5320-331X, Armario Garcia, Antonio|||0000-0001-9524-3635, Cabezas, Ángel|||0000-0001-8114-0264, De Arriba-Arnau, Aida|||0000-0002-7877-7341, Nadal i Alemany, Roser|||0000-0001-8972-2525, Martorell, Lourdes|||0000-0003-4999-2197
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:233668
Acceso en línea:https://ddd.uab.cat/record/233668
https://dx.doi.org/urn:doi:10.3390/ijerph17207600
Access Level:acceso abierto
Palabra clave:Sleep quality
Memory
Cortisol
Trait anxiety
Descripción
Sumario:Sleep plays a crucial role in cognitive processes. Sleep and wake memory consolidation seem to be regulated by glucocorticoids, pointing out the potential role of the hypothalamic-pituitary-adrenal (HPA) axis in the relationship between sleep quality and cognitive abilities. Trait anxiety is another factor that is likely to moderate the relationship between sleep and cognition, because poorer sleep quality and subtle HPA axis abnormalities have been reported in people with high trait anxiety. The current study aimed to explore whether HPA axis activity or trait anxiety moderate the relationship between sleep quality and cognitive abilities in healthy individuals. We studied 203 healthy individuals. We measured verbal and visual memory, working memory, processing speed, attention and executive function. Sleep quality was assessed with the Pittsburgh Sleep Quality Index. Trait anxiety was assessed with the State-Trait Anxiety Inventory. HPA axis measures included the cortisol awakening response (CAR), diurnal cortisol slope and cortisol levels during the day. Multiple linear regression analyses explored the relationship between sleep quality and cognition and tested potential moderating effects by HPA axis measures and trait anxiety. Poor sleep quality was associated with poorer performance in memory, processing speed and executive function tasks. In people with poorer sleep quality, a blunted CAR was associated with poorer verbal and visual.

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