Vaccination Recommendations in Patients With Atopic Dermatitis Treated With Inhibitors

Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine administration. This document aims to provi...

Descripción completa

Detalles Bibliográficos
Autores: Ara-Martín, Mariano, Moreno, Carol|||0000-0003-3275-0271, Ruíz Villaverde, Ricardo|||0000-0002-0381-6174, Serra Baldrich, Esther|||0000-0001-7603-0300, Hernández-Martín, Irene, del Pilar Fortes, Maria
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:dnet:uabarcelona_::d35d3d88453ad8168a48cf8409127aed
Acceso en línea:https://ddd.uab.cat/record/326348
https://dx.doi.org/urn:doi:10.1111/ijd.70033
Access Level:acceso abierto
Palabra clave:Atopic dermatitis
JAK inhibitors
Recommendations
Vaccination
Descripción
Sumario:Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine administration. This document aims to provide dermatologists and other healthcare practitioners with comprehensive practical vaccination recommendations for adults and adolescent patients with atopic dermatitis who are receiving or are about to receive treatment with JAK inhibitors. While inactivated vaccines are safe and recommended during JAK treatment, live attenuated vaccines are contraindicated unless treatment is temporarily discontinued according to clinical guidelines. It is crucial to follow vaccination guidelines established by official agencies and tailor them to individual patient needs. Careful consideration and follow-up are essential to ensure patient safety and optimal therapeutic outcomes. Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors.