Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age

Objectives: to compare subjective tolerance and secondary adverse events to bowel cleansing prior to colonoscopy with polyethylene glycol (PEG) and sodium phosphate (NaP) in adult patients and in those 65 or more years old. Material and methods: retrospective matched study, choosing 140 patients amo...

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Autores: Rodríguez Alcalde, D., Marín Gabriel, José Carlos, Marín Gabriel, J. C., Rodríguez Muñoz, S., Cruz Bértolo, J. de la, Barreales Valbuena, M., Manzano Alonso, M. L., Solís Herruzo, José Antonio
Tipo de recurso: artículo
Fecha de publicación:2008
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/130720
Acceso en línea:https://hdl.handle.net/20.500.14352/130720
Access Level:acceso abierto
Palabra clave:Gastroenterología y hepatología
3205.03 Gastroenterología
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spelling Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of ageRodríguez Alcalde, D.Marín Gabriel, José CarlosMarín Gabriel, J. C.Rodríguez Muñoz, S.Cruz Bértolo, J. de laBarreales Valbuena, M.Manzano Alonso, M. L.Solís Herruzo, José AntonioGastroenterología y hepatología3205.03 GastroenterologíaObjectives: to compare subjective tolerance and secondary adverse events to bowel cleansing prior to colonoscopy with polyethylene glycol (PEG) and sodium phosphate (NaP) in adult patients and in those 65 or more years old. Material and methods: retrospective matched study, choosing 140 patients among all of those who underwent colonoscopy from March 2004 to May 2005. We investigated the presence of the next adverse events during bowel preparation: Fever, low digestive bleeding, abdominal pain, perianal pain, nausea, vomiting, thirst, somnolence, agitation, tremor and convulsions. We considered bad objective tolerance if the patient presented any one of these events. We also asked patients about subjective tolerance to preparation. Results: seventy patients prepared with PEG and seventy with NaP were included (69 women and 71 men, mean age 60,6 ± 14,8 years). There was no relationship between subjective tolerance or the presence of adverse events and bowel cleansing with any of the products in general population or in elderly patients (p = 0,09 and p = 0,45 in the elderly). However, patients prepared with NaP showed more nausea than those who employed PEG (p < 0,009), overall women of 65 or more years old. There were no severe adverse events in patients prepared with NaP. Elderly showed better tolerance than younger patients, and women worst tolerance than men, irrespective of the lavage preparation employed. Patients prepared with PEG unfinished bowel cleansing more frequently than those with NaP. Cleanliness achieved with NaP was significantly better than that obtained with PEG. Conclusions: bowel cleansing prior to colonoscopy with NaP is as well tolerated, safe and effective as with PEG, even in elderly healthy patients, although it causes more nausea. Cleanliness with NaP is better than that achieved with PEG.AranUniversidad Complutense de Madrid20082008-01-0120082008-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/130720reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1307202026-06-02T12:44:21Z
dc.title.none.fl_str_mv Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
title Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
spellingShingle Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
Rodríguez Alcalde, D.
Gastroenterología y hepatología
3205.03 Gastroenterología
title_short Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
title_full Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
title_fullStr Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
title_full_unstemmed Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
title_sort Tolerability, safety, and efficacy of sodium phosphate preparation for colonoscopy: The role of age
dc.creator.none.fl_str_mv Rodríguez Alcalde, D.
Marín Gabriel, José Carlos
Marín Gabriel, J. C.
Rodríguez Muñoz, S.
Cruz Bértolo, J. de la
Barreales Valbuena, M.
Manzano Alonso, M. L.
Solís Herruzo, José Antonio
author Rodríguez Alcalde, D.
author_facet Rodríguez Alcalde, D.
Marín Gabriel, José Carlos
Marín Gabriel, J. C.
Rodríguez Muñoz, S.
Cruz Bértolo, J. de la
Barreales Valbuena, M.
Manzano Alonso, M. L.
Solís Herruzo, José Antonio
author_role author
author2 Marín Gabriel, José Carlos
Marín Gabriel, J. C.
Rodríguez Muñoz, S.
Cruz Bértolo, J. de la
Barreales Valbuena, M.
Manzano Alonso, M. L.
Solís Herruzo, José Antonio
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv Gastroenterología y hepatología
3205.03 Gastroenterología
topic Gastroenterología y hepatología
3205.03 Gastroenterología
description Objectives: to compare subjective tolerance and secondary adverse events to bowel cleansing prior to colonoscopy with polyethylene glycol (PEG) and sodium phosphate (NaP) in adult patients and in those 65 or more years old. Material and methods: retrospective matched study, choosing 140 patients among all of those who underwent colonoscopy from March 2004 to May 2005. We investigated the presence of the next adverse events during bowel preparation: Fever, low digestive bleeding, abdominal pain, perianal pain, nausea, vomiting, thirst, somnolence, agitation, tremor and convulsions. We considered bad objective tolerance if the patient presented any one of these events. We also asked patients about subjective tolerance to preparation. Results: seventy patients prepared with PEG and seventy with NaP were included (69 women and 71 men, mean age 60,6 ± 14,8 years). There was no relationship between subjective tolerance or the presence of adverse events and bowel cleansing with any of the products in general population or in elderly patients (p = 0,09 and p = 0,45 in the elderly). However, patients prepared with NaP showed more nausea than those who employed PEG (p < 0,009), overall women of 65 or more years old. There were no severe adverse events in patients prepared with NaP. Elderly showed better tolerance than younger patients, and women worst tolerance than men, irrespective of the lavage preparation employed. Patients prepared with PEG unfinished bowel cleansing more frequently than those with NaP. Cleanliness achieved with NaP was significantly better than that obtained with PEG. Conclusions: bowel cleansing prior to colonoscopy with NaP is as well tolerated, safe and effective as with PEG, even in elderly healthy patients, although it causes more nausea. Cleanliness with NaP is better than that achieved with PEG.
publishDate 2008
dc.date.none.fl_str_mv 2008
2008-01-01
2008
2008-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/130720
url https://hdl.handle.net/20.500.14352/130720
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Aran
publisher.none.fl_str_mv Aran
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.81155

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