Effect of estrogen and insulin sensitivity due to exercise training with dual intensities in female rats with estradiol valerate-induced PCOS
[eng] Background: Exercise training can improve polycystic ovary syndrome (PCOS). However, the effect of various intensities of exercise training is unclear, hence the purpose of this study was to evaluate the effect of exercise training with dual intensities on estrogen and insuli...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad de las Islas Baleares |
| Repositorio: | Biblioteca Digital de les Illes Balears |
| OAI Identifier: | medicinaBalear:AJHS_Medicina_Balear_2021v36n3p088 |
| Acceso en línea: | http://ibdigital.uib.es/greenstone/sites/oai-site/collect/medicinaBalear/index/assoc/AJHS_Med/icina_Ba/lear_202/1v36n3p0/88.dir/AJHS_Medicina_Balear_2021v36n3p088.pdf http://ibdigital.uib.es/greenstone/library/collection/medicinaBalear/document/AJHS_Medicina_Balear_2021v36n3p088 |
| Access Level: | acceso abierto |
| Palabra clave: | Polycystic ovary syndrome Health Sciences |
| Sumario: | [eng] Background: Exercise training can improve polycystic ovary syndrome (PCOS). However, the effect of various intensities of exercise training is unclear, hence the purpose of this study was to evaluate the effect of exercise training with dual intensities on estrogen and insulin sensitivity in female rats with estradiol valerate-induced PCOS. Methods: In this semi experimental study, forty adult (Wistar rats weight: 180±20 gr) after induction of PCOS, were divided into four groups (n=10):healthy control (HC), polycystic control (PC), low intensity training (LI) and moderate intensity training (MI) groups. Exercise training consisted of eight-week exercise with 50-55% maximal oxygen consumption (20m/min speed) and 70-75% maximal oxygen consumption (28m/min speed), 3 days a week for 60 minutes. Data analysis was performed using SPSS software (version 16.0, SPSS). One-was ANOVA test was used for data analysis. The level of significance was set at p<0.05. Results: Significant difference was observed between glucose concentration of MI and PC (p=0.039), also there was significant difference between LI and PC (p=0.005). Insulin significantly redreased in MI compared to PC (p=0.002). Also, significant difference was found between LI and PC (p=0.005). Conclusion: It seems that exercise training with low and moderate intensity may reduce insulin and glucose level. Low intensity may improve insulin sensitivity, and can be considered as a non-pharmacological treatment method to regulate glucose hemostasis in polycystic ovary syndrome patients. |
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