Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion

Rosehips, particularly dog rose fruits (Rosa canina L.), are a great source of antioxidant compounds, mainly phenolics. However, their health benefits directly depend on the bioaccessibility of these compounds affected by gastrointestinal digestion. Thus, the purpose of this research was to study th...

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Autores: Odriozola Serrano, Isabel, Nogueira, Danielle P., Esparza-Catalan, Irene, Vaz, Ana A., Jiménez-Moreno, Nerea, Martín Belloso, Olga, Ancín-Azpilicueta, Carmen
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10459.1/463584
Acceso en línea:https://doi.org/10.3390/antiox12051035
https://hdl.handle.net/10459.1/463584
Access Level:acceso abierto
Palabra clave:Antioxidant activity
Bioaccessibility
In vitro digestion
rosehips
Fenols
Antioxidants
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spelling Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestionOdriozola Serrano, IsabelNogueira, Danielle P.Esparza-Catalan, IreneVaz, Ana A.Jiménez-Moreno, NereaMartín Belloso, OlgaAncín-Azpilicueta, CarmenAntioxidant activityBioaccessibilityIn vitro digestionrosehipsFenolsAntioxidantsRosehips, particularly dog rose fruits (Rosa canina L.), are a great source of antioxidant compounds, mainly phenolics. However, their health benefits directly depend on the bioaccessibility of these compounds affected by gastrointestinal digestion. Thus, the purpose of this research was to study the impact of gastrointestinal and colonic in vitro digestions on the concentration of total and individual bioaccessible phenolic compounds from a hydroalcoholic extract of rosehips (Rosa canina) and also their antioxidant capacity. A total of 34 phenolic compounds were detected in the extracts using UPLC-MS/MS. Ellagic acid, taxifolin, and catechin were the most abundant compounds in the free fraction, while gallic and p-coumaric acids were the main compounds in the bound phenolic fraction. Gastric digestion negatively affected the content of free phenolic compounds and the antioxidant activity measured using the DPPH radical method. However, there was an enhancement of antioxidant properties in terms of phenolic content and antioxidant activity (DPPH (2,2-diphenyl-1-picrylhydrazyl): 18.01 ± 4.22 mmol Trolox Equivalent (TE)/g; FRAP (Ferric Reducing Antioxidant Power): 7.84 ± 1.83 mmol TE/g) after the intestinal stage. The most bioaccessible phenolic compounds were flavonols (73.3%) and flavan-3-ols (71.4%). However, the bioaccessibility of phenolic acids was 3%, probably indicating that most of the phenolic acids were still bound to other components of the extract. Ellagic acid is an exception since it presented a high bioaccessibility (93%) as it was mainly found in the free fraction of the extract. Total phenolic content decreased after in vitro colonic digestion, probably due to chemical transformations of the phenolic compounds by gut microbiota. These results demonstrated that rosehip extracts have a great potential to be used as a functional ingredient.This research was funded by European Union’s H2020 research and innovation program under Marie Sklodowska-Curie grant number 801586, and by Ministerio de Ciencia y Tecnología, Gobierno de España: Project number AGLRTI-2018-094268-B-C21.MDPI2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://doi.org/10.3390/antiox12051035https://hdl.handle.net/10459.1/463584reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)Inglésinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094268-B-C21Reproducció del document publicat a https://doi.org/10.3390/antiox12051035Antioxidants, 2023, vol. 12, núm.5, p. 1-17801586cc-by (c) Odriozola et al., 2023Attribution 4.0 Internationalinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/oai:recercat.cat:10459.1/4635842026-05-29T05:05:01Z
dc.title.none.fl_str_mv Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
title Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
spellingShingle Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
Odriozola Serrano, Isabel
Antioxidant activity
Bioaccessibility
In vitro digestion
rosehips
Fenols
Antioxidants
title_short Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
title_full Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
title_fullStr Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
title_full_unstemmed Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
title_sort Stability and bioaccessibility of phenolic compounds in rosehip extracts during in vitro digestion
dc.creator.none.fl_str_mv Odriozola Serrano, Isabel
Nogueira, Danielle P.
Esparza-Catalan, Irene
Vaz, Ana A.
Jiménez-Moreno, Nerea
Martín Belloso, Olga
Ancín-Azpilicueta, Carmen
author Odriozola Serrano, Isabel
author_facet Odriozola Serrano, Isabel
Nogueira, Danielle P.
Esparza-Catalan, Irene
Vaz, Ana A.
Jiménez-Moreno, Nerea
Martín Belloso, Olga
Ancín-Azpilicueta, Carmen
author_role author
author2 Nogueira, Danielle P.
Esparza-Catalan, Irene
Vaz, Ana A.
Jiménez-Moreno, Nerea
Martín Belloso, Olga
Ancín-Azpilicueta, Carmen
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Antioxidant activity
Bioaccessibility
In vitro digestion
rosehips
Fenols
Antioxidants
topic Antioxidant activity
Bioaccessibility
In vitro digestion
rosehips
Fenols
Antioxidants
description Rosehips, particularly dog rose fruits (Rosa canina L.), are a great source of antioxidant compounds, mainly phenolics. However, their health benefits directly depend on the bioaccessibility of these compounds affected by gastrointestinal digestion. Thus, the purpose of this research was to study the impact of gastrointestinal and colonic in vitro digestions on the concentration of total and individual bioaccessible phenolic compounds from a hydroalcoholic extract of rosehips (Rosa canina) and also their antioxidant capacity. A total of 34 phenolic compounds were detected in the extracts using UPLC-MS/MS. Ellagic acid, taxifolin, and catechin were the most abundant compounds in the free fraction, while gallic and p-coumaric acids were the main compounds in the bound phenolic fraction. Gastric digestion negatively affected the content of free phenolic compounds and the antioxidant activity measured using the DPPH radical method. However, there was an enhancement of antioxidant properties in terms of phenolic content and antioxidant activity (DPPH (2,2-diphenyl-1-picrylhydrazyl): 18.01 ± 4.22 mmol Trolox Equivalent (TE)/g; FRAP (Ferric Reducing Antioxidant Power): 7.84 ± 1.83 mmol TE/g) after the intestinal stage. The most bioaccessible phenolic compounds were flavonols (73.3%) and flavan-3-ols (71.4%). However, the bioaccessibility of phenolic acids was 3%, probably indicating that most of the phenolic acids were still bound to other components of the extract. Ellagic acid is an exception since it presented a high bioaccessibility (93%) as it was mainly found in the free fraction of the extract. Total phenolic content decreased after in vitro colonic digestion, probably due to chemical transformations of the phenolic compounds by gut microbiota. These results demonstrated that rosehip extracts have a great potential to be used as a functional ingredient.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3390/antiox12051035
https://hdl.handle.net/10459.1/463584
url https://doi.org/10.3390/antiox12051035
https://hdl.handle.net/10459.1/463584
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094268-B-C21
Reproducció del document publicat a https://doi.org/10.3390/antiox12051035
Antioxidants, 2023, vol. 12, núm.5, p. 1-17
801586
dc.rights.none.fl_str_mv cc-by (c) Odriozola et al., 2023
Attribution 4.0 International
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
rights_invalid_str_mv cc-by (c) Odriozola et al., 2023
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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