Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain

The monitoring of antimicrobial susceptibility of pig pathogens is critical to optimize antimicrobial treatments and prevent development of resistance with a one-health approach. The aim of this study was to investigate the antimicrobial susceptibility patterns of swine respiratory pathogens in Spai...

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Autores: Vilaró, Anna, Novell, Elena, Tarancón, Vicens, Balielles, Jordi, Vilalta, Carles, Martínez, Sonia, Fraile Sauce, Lorenzo José
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10459.1/69312
Acceso en línea:https://doi.org/10.3390/antibiotics9070402
http://hdl.handle.net/10459.1/69312
Access Level:acceso abierto
Palabra clave:Antimicrobial susceptibility
Swine
Respiratory pathogens
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spelling Antimicrobial susceptibility pattern of porcine respiratory bacteria in SpainVilaró, AnnaNovell, ElenaTarancón, VicensBalielles, JordiVilalta, CarlesMartínez, SoniaFraile Sauce, Lorenzo JoséAntimicrobial susceptibilitySwineRespiratory pathogensThe monitoring of antimicrobial susceptibility of pig pathogens is critical to optimize antimicrobial treatments and prevent development of resistance with a one-health approach. The aim of this study was to investigate the antimicrobial susceptibility patterns of swine respiratory pathogens in Spain from 2017 to 2019. Bacterial isolation and identification were carried out following standardized methods from samples coming from sacrificed or recently deceased pigs with acute clinical signs compatible with respiratory tract infections. Minimum inhibitory concentration (MIC) values were determined using the broth microdilution method containing a total of 10 and 7-8 antimicrobials/concentrations respectively, in accordance with the recommendations presented by the Clinical and Laboratory Standards Institute (CLSI). The obtained antimicrobial susceptibility varies between pig respiratory pathogens. Actinobacillus pleuropneumoniae (APP) and Pasteurella multocida (PM) were highly susceptible (≥90%) to ceftiofur, florfenicol and macrolides (tilmicosin, tildipirosin and tulathromycin). However, the antimicrobial susceptibility was intermediate (>60% but <90%) for amoxicillin and enrofloxacin in the case of APP and sulfamethoxazole/trimethropim and tiamulin in the case of PM. Both bacteria showed low (<60%) antimicrobial susceptibility to doxycycline. Finally, Bordetella bronchiseptica was highly susceptible only to tildipirosin and tulathromycin (100%) and its susceptibility for florfenicol was close to 50% and <30% for the rest of the antimicrobial families tested. These results emphasize the need of determining antimicrobial susceptibility in pig respiratory cases in order to optimize the antimicrobial treatment in a case-by-case scenario.MDPI2020202020202020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.3390/antibiotics9070402http://hdl.handle.net/10459.1/69312http://hdl.handle.net/10459.1/69312reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.3390/antibiotics9070402Antibiotics-Basel, 2020, vol. 9, num. 7, p. 402cc-by (c) Vilaró, Anna et al., 2020info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/oai:recercat.cat:10459.1/693122026-05-29T05:05:01Z
dc.title.none.fl_str_mv Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
title Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
spellingShingle Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
Vilaró, Anna
Antimicrobial susceptibility
Swine
Respiratory pathogens
title_short Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
title_full Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
title_fullStr Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
title_full_unstemmed Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
title_sort Antimicrobial susceptibility pattern of porcine respiratory bacteria in Spain
dc.creator.none.fl_str_mv Vilaró, Anna
Novell, Elena
Tarancón, Vicens
Balielles, Jordi
Vilalta, Carles
Martínez, Sonia
Fraile Sauce, Lorenzo José
author Vilaró, Anna
author_facet Vilaró, Anna
Novell, Elena
Tarancón, Vicens
Balielles, Jordi
Vilalta, Carles
Martínez, Sonia
Fraile Sauce, Lorenzo José
author_role author
author2 Novell, Elena
Tarancón, Vicens
Balielles, Jordi
Vilalta, Carles
Martínez, Sonia
Fraile Sauce, Lorenzo José
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Antimicrobial susceptibility
Swine
Respiratory pathogens
topic Antimicrobial susceptibility
Swine
Respiratory pathogens
description The monitoring of antimicrobial susceptibility of pig pathogens is critical to optimize antimicrobial treatments and prevent development of resistance with a one-health approach. The aim of this study was to investigate the antimicrobial susceptibility patterns of swine respiratory pathogens in Spain from 2017 to 2019. Bacterial isolation and identification were carried out following standardized methods from samples coming from sacrificed or recently deceased pigs with acute clinical signs compatible with respiratory tract infections. Minimum inhibitory concentration (MIC) values were determined using the broth microdilution method containing a total of 10 and 7-8 antimicrobials/concentrations respectively, in accordance with the recommendations presented by the Clinical and Laboratory Standards Institute (CLSI). The obtained antimicrobial susceptibility varies between pig respiratory pathogens. Actinobacillus pleuropneumoniae (APP) and Pasteurella multocida (PM) were highly susceptible (≥90%) to ceftiofur, florfenicol and macrolides (tilmicosin, tildipirosin and tulathromycin). However, the antimicrobial susceptibility was intermediate (>60% but <90%) for amoxicillin and enrofloxacin in the case of APP and sulfamethoxazole/trimethropim and tiamulin in the case of PM. Both bacteria showed low (<60%) antimicrobial susceptibility to doxycycline. Finally, Bordetella bronchiseptica was highly susceptible only to tildipirosin and tulathromycin (100%) and its susceptibility for florfenicol was close to 50% and <30% for the rest of the antimicrobial families tested. These results emphasize the need of determining antimicrobial susceptibility in pig respiratory cases in order to optimize the antimicrobial treatment in a case-by-case scenario.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3390/antibiotics9070402
http://hdl.handle.net/10459.1/69312
http://hdl.handle.net/10459.1/69312
url https://doi.org/10.3390/antibiotics9070402
http://hdl.handle.net/10459.1/69312
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/antibiotics9070402
Antibiotics-Basel, 2020, vol. 9, num. 7, p. 402
dc.rights.none.fl_str_mv cc-by (c) Vilaró, Anna et al., 2020
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
rights_invalid_str_mv cc-by (c) Vilaró, Anna et al., 2020
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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