Effects of vaccination with Brucella melitensis, strains Rev 1 ΔeryCD and Rev 1, on the reproductive system of young male goats

[EN]: The present study evaluates the effects of vaccination with Brucella melitensis strains Rev 1 ΔeryCD and Rev 1 on the reproductive system of male goats. Three groups, each of them consisting of 15 six-month-old brucellosis-free male goats, were studied. The first group was vaccinated with the...

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Detalles Bibliográficos
Autores: López Vásquez, Isauro Alejandro, Palomares Resendiz, Erika Gabriela, Gutiérrez Hernández, José Luis, Garrido Fariña, Germán Isauro, Olmos Espejel, José de Jesús, Hernández-Castro, Rigoberto, Sangari, Félix J., Suárez-Güemes, Francisco, Díaz Aparicio, Efrén
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/382545
Acceso en línea:http://hdl.handle.net/10261/382545
Access Level:acceso abierto
Palabra clave:Brucellosis
Male goats
Vaccination
Rev 1
Rev 1 ΔeryCD
Brucelosis
Machos cabríos
Vacunación
Descripción
Sumario:[EN]: The present study evaluates the effects of vaccination with Brucella melitensis strains Rev 1 ΔeryCD and Rev 1 on the reproductive system of male goats. Three groups, each of them consisting of 15 six-month-old brucellosis-free male goats, were studied. The first group was vaccinated with the Rev 1 ΔeryCD strain, the second group received Rev 1 and the third group was inoculated with sterile physiological saline solution. The dose of both strains was of 1 × 109 CFU/ml. Over the course of the five months of this study, three males from each group were euthanized every month. Their reproductive tracts, spleens, and lymph nodes were collected to analyze serology, bacteriology PCR, histology, and immunohistochemistry. Results show that vaccination with B. melitensis strains Rev 1 ΔeryCD and Rev 1 does not harm the reproductive system of male goats. Strain B. melitensis Rev 1 ΔeryCD displayed a lower capacity to colonize the reproductive tract than strain Rev 1, which was attributed to its limited catabolic action toward erythritol.

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