Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study

Objective: Information about prognostic outcomes can be of great help for people with prediabetes and for physicians in the face of scientific controversy about the cutoff point for definingprediabetes. We aimed to estimate different prognostic outcomes in people with prediabetes. Design: Prospectiv...

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Authors: Regidor, Enrique, Cea Soriano, Lucía, Ruiz García, Antonio, Goday, Albert, Carabantes, David, Díez Espino, Javier, Artola, Sara, Franch Nadal, Josep, PREDAPS Study Group
Format: article
Publication Date:2021
Country:España
Institution:Universidad Europea (UEM)
Repository:ABACUS. Repositorio de Producción Científica
Language:English
OAI Identifier:oai:abacus.universidadeuropea.com:11268/12254
Online Access:http://hdl.handle.net/11268/12254
Access Level:Open access
Keyword:Estado Prediabético
Enfermedades Metabólicas
Enfermedad nutricional
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spelling Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort studyRegidor, EnriqueCea Soriano, LucíaRuiz García, AntonioGoday, AlbertCarabantes, DavidDíez Espino, JavierArtola, SaraFranch Nadal, JosepPREDAPS Study GroupEstado PrediabéticoEnfermedades MetabólicasEnfermedad nutricionalObjective: Information about prognostic outcomes can be of great help for people with prediabetes and for physicians in the face of scientific controversy about the cutoff point for definingprediabetes. We aimed to estimate different prognostic outcomes in people with prediabetes. Design: Prospective cohort of subjects with prediabetes according to American Diabetes Association guidelines. Main Outcome measures: The probabilities of diabetes onset versus non-onset, the oddsagainst diabetes onset, and the probability of reverting to normoglycemia according to different prediabetes categories were calculated. Results: The odds against diabetes onset ranged from 29:1 in individuals with isolated FPG of100–109mg/dL to 1:1 in individuals with FPG 110–125mg/dL plus HbA1c 6.0–6.4%. The probability of reversion to normoglycemia was 31.2% (95% CI 24.0–39.6) in those with isolated FPG100–109mg/dL and 6.2% (95% CI 1.4–10.0) in those with FPG 110–125mg/dL plus HbA1c6.0–6.4%. Of every 100 participants in the first group, 97 did not develop diabetes and 31reverted to normoglycemia, while in the second group those figures were 52 and 6. Conclusions: Using odds of probabilities and absolute numbers might be useful for people with prediabetes and physicians to share decisions on potential interventions.20232023-08-0420212021-01-0120212021-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/11268/12254reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/122542026-06-11T12:41:27Z
dc.title.none.fl_str_mv Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
title Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
spellingShingle Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
Regidor, Enrique
Estado Prediabético
Enfermedades Metabólicas
Enfermedad nutricional
title_short Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
title_full Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
title_fullStr Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
title_full_unstemmed Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
title_sort Classifying and communicating risks in prediabetes according to fastingglucose and/or glycated hemoglobin: PREDAPS cohort study
dc.creator.none.fl_str_mv Regidor, Enrique
Cea Soriano, Lucía
Ruiz García, Antonio
Goday, Albert
Carabantes, David
Díez Espino, Javier
Artola, Sara
Franch Nadal, Josep
PREDAPS Study Group
author Regidor, Enrique
author_facet Regidor, Enrique
Cea Soriano, Lucía
Ruiz García, Antonio
Goday, Albert
Carabantes, David
Díez Espino, Javier
Artola, Sara
Franch Nadal, Josep
PREDAPS Study Group
author_role author
author2 Cea Soriano, Lucía
Ruiz García, Antonio
Goday, Albert
Carabantes, David
Díez Espino, Javier
Artola, Sara
Franch Nadal, Josep
PREDAPS Study Group
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Estado Prediabético
Enfermedades Metabólicas
Enfermedad nutricional
topic Estado Prediabético
Enfermedades Metabólicas
Enfermedad nutricional
description Objective: Information about prognostic outcomes can be of great help for people with prediabetes and for physicians in the face of scientific controversy about the cutoff point for definingprediabetes. We aimed to estimate different prognostic outcomes in people with prediabetes. Design: Prospective cohort of subjects with prediabetes according to American Diabetes Association guidelines. Main Outcome measures: The probabilities of diabetes onset versus non-onset, the oddsagainst diabetes onset, and the probability of reverting to normoglycemia according to different prediabetes categories were calculated. Results: The odds against diabetes onset ranged from 29:1 in individuals with isolated FPG of100–109mg/dL to 1:1 in individuals with FPG 110–125mg/dL plus HbA1c 6.0–6.4%. The probability of reversion to normoglycemia was 31.2% (95% CI 24.0–39.6) in those with isolated FPG100–109mg/dL and 6.2% (95% CI 1.4–10.0) in those with FPG 110–125mg/dL plus HbA1c6.0–6.4%. Of every 100 participants in the first group, 97 did not develop diabetes and 31reverted to normoglycemia, while in the second group those figures were 52 and 6. Conclusions: Using odds of probabilities and absolute numbers might be useful for people with prediabetes and physicians to share decisions on potential interventions.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01
2021
2021-01-01
2023
2023-08-04
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/11268/12254
url http://hdl.handle.net/11268/12254
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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