Reverse myocardial remodeling following valve replacement in patients with aortic stenosis

Background Left ventricular (LV) hypertrophy, a key process in human cardiac disease, results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis). Objectives This study sought to investigate whether human myocardial interstitial fibrosis in aortic stenosis (AS) is...

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Autores: Treibel, T.A. (Thomas A.)|||/items/07a51ca9-29c4-42e6-856e-db9593c33fd4, Kozor, R. (Rebecca)|||/items/6ecbcd45-bfa1-4942-9d89-f47001ddcb77, Schofield, R.S. (Rebecca S.)|||/items/65f6e5a2-8c01-48d6-86b1-6fb9336863ab, Benedetti, G. (Giulia)|||/items/10eb0405-7043-49c5-94f3-f51302000963, Fontana, M. (Marianna)|||/items/c282fcc9-f89e-476a-b5a4-87b3f6e3849a, Bhuva, A.N. (Anish N.)|||/items/248d021d-3a19-491c-bf90-1cd8817ad27d, Sheikh, A. (Amir)|||/items/ad5ef38c-92ca-40e5-9ad3-f6f76b463a38, Lopez-Salazar, M.B. (María Begoña)|||/items/153e0e37-14b0-403e-afab-8af00c4edde0, Gonzalez, A. (Arantxa)|||/items/9c64c0f4-66b4-4b51-8593-0e50c091a515, Manisty, C. (Charlotte)|||/items/6d2c6289-e0b4-4e30-887f-ab301876f201, Lloyd, G. (Guy)|||/items/a25f3969-46d5-41f7-a4ef-cc980052053c, Kellman, P. (Peter)|||/items/6168fee4-8b96-4039-9c4f-3acc65691b00, Diez, J. (Javier)|||/items/adeda0be-cebc-4240-899c-ab26f05dea9c, Moon, J.C. (James C.)|||/items/7c39855a-3b38-428d-b08e-379caa124ea3
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/65657
Acceso en línea:https://hdl.handle.net/10171/65657
Access Level:acceso abierto
Palabra clave:Left ventricular (LV)
Hypertrophy
Interstitial fibrosis
Extracellular matrix expansion
Descripción
Sumario:Background Left ventricular (LV) hypertrophy, a key process in human cardiac disease, results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis). Objectives This study sought to investigate whether human myocardial interstitial fibrosis in aortic stenosis (AS) is plastic and can regress.

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