Enzyme-Powered Porous Micromotors Built from a Hierarchical Micro- and Mesoporous UiO-Type Metal–Organic Framework
Here, we report the design, synthesis, and functional testing of enzyme-powered porous micromotors built from a metal–organic framework (MOF). We began by subjecting a presynthesized microporous UiO-type MOF to ozonolysis, to confer it with mesopores sufficiently large to adsorb and host the enzyme...
| Autores: | , , , , , , , , |
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| Formato: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2020 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/180514 |
| Acesso em linha: | https://hdl.handle.net/2445/180514 |
| Access Level: | acceso abierto |
| Palavra-chave: | Polímers Programació orientada a l'objecte (Informàtica) Polymers Object-oriented programming (Computer science) |
| Resumo: | Here, we report the design, synthesis, and functional testing of enzyme-powered porous micromotors built from a metal–organic framework (MOF). We began by subjecting a presynthesized microporous UiO-type MOF to ozonolysis, to confer it with mesopores sufficiently large to adsorb and host the enzyme catalase (size: 6–10 nm). We then encapsulated catalase inside the mesopores, observing that they are hosted in those mesopores located at the subsurface of the MOF crystals. In the presence of H2O2 fuel, MOF motors (or MOFtors) exhibit jet-like propulsion enabled by enzymatic generation of oxygen bubbles. Moreover, thanks to their hierarchical pore system, the MOFtors retain sufficient free space for adsorption of additional targeted species, which we validated by testing a MOFtor for removal of rhodamine B during self-propulsion. |
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