An association analysis between a polymorphism in the SEC24A gene and lipid traits recorded in Duroc pigs
By regulating the expression of low-density lipoprotein receptors (LDLR), the SEC24A protein modulates the clearance of plasma cholesterol in mice. The whole-genome sequencing of five Duroc boars that sired a Duroc purebred experimental population (LIPGEN population, 350 individuals) revealed the se...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:255925 |
| Acceso en línea: | https://ddd.uab.cat/record/255925 https://dx.doi.org/urn:doi:10.1080/1828051X.2021.1951129 |
| Access Level: | acceso abierto |
| Palabra clave: | Nonsense mutation Pig Lipid traits Skeletal muscle |
| Sumario: | By regulating the expression of low-density lipoprotein receptors (LDLR), the SEC24A protein modulates the clearance of plasma cholesterol in mice. The whole-genome sequencing of five Duroc boars that sired a Duroc purebred experimental population (LIPGEN population, 350 individuals) revealed the segregation of one putative nonsense mutation located at the SEC24A (rs336401826, c.44G. |
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