Awake prone positioning in acute hypoxaemic respiratory failure: An international expert guidance

Background: Awake prone positioning (APP) of non-intubated patients with acute hypoxaemic respiratory failure (AHRF) has been inconsistently adopted into routine care of patients with COVID-19, likely due to apparent conflicting evidence from recent trials. This short guideline aims to provide evide...

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Detalhes bibliográficos
Autores: Pavlov, I, Li, J, Kharat, A, Luo, J, Ibarra-Estrada, M, Perez, Y, McNicolas, B, Poole, D, Roca, O, Vines, D, Tavernier, E, Allen, T, Shyamsundar, M, Ehrmann, S, Simpson, SQ, Guerin, C, Laffey, JG
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repositorio:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:oai:i3pt.fundanetsuite.com:p4151
Acesso em linha:https://i3pt.portalinvestigacion.com/publicaciones/4151
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85168737793&doi=10.1016%2fj.jcrc.2023.154401&partnerID=40&md5=3a66e0044f377b501d8332257826fab8
Access Level:acceso abierto
Palavra-chave:COVID-19
Awake prone positioning
Prone position
Acute hypoxaemic respiratory failure
Guideline
High flow nasal cannula
Oxygen therapy
Non-invasive ventilation
Descrição
Resumo:Background: Awake prone positioning (APP) of non-intubated patients with acute hypoxaemic respiratory failure (AHRF) has been inconsistently adopted into routine care of patients with COVID-19, likely due to apparent conflicting evidence from recent trials. This short guideline aims to provide evidence-based recommendations for the use of APP in various clinical scenarios.Methods: An international multidisciplinary panel, assembled for their expertise and representativeness, and supported by a methodologist, performed a systematic literature search, summarized the available evidence derived from randomized clinical trials, and developed recommendations using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodology.Results: The panel strongly recommends that APP rather than standard supine care be used in patients with COVID-19 receiving advanced respiratory support (high-flow nasal cannula, continuous positive airway pressure or non-invasive ventilation). Due to lack of evidence from randomized controlled trials, the panel provides no recommendation on the use of APP in patients with COVID-19 supported with conventional oxygen therapy, nor in patients with AHRF due to causes other than COVID-19.Conclusion: APP should be routinely implemented in patients with COVID-19 receiving advanced respiratory support.