Additional file 4 of Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia [Dataset]

Additional file 4: Figure S4. a, Representative two-color contour plots of lymphoid populations in liver and spleen from 2 wk-old mice according to the expression of CD19 and CD5 and within the CD19 + CD5+ population according to the expression of CD21, B220, CD24, CD23 and CD38 markers. b, Column p...

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Detalles Bibliográficos
Autores: Hortal, Alejandro, Oeste, Clara L., Cifuentes, Claudia, Alcoceba, Miguel, Fernández-Pisonero, Isabel, Clavaín, Laura, Tercero, Rut, Mendoza, Pilar, Domínguez, Verónica, García-Flores, Marta, Pintado, Belén, Abia, David, García-Macías, Carmen, Navarro-Bailón, Almudena, Bustelo, Xosé R., González, Marcos, Alarcón, Balbino
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/329850
Acceso en línea:http://hdl.handle.net/10261/329850
Access Level:acceso abierto
Palabra clave:RRAS2
RAS proteins
B cells
Lymphoid malignancies
Chronic lymphocytic leukemia
B cell receptor
PI3K pathway
Descripción
Sumario:Additional file 4: Figure S4. a, Representative two-color contour plots of lymphoid populations in liver and spleen from 2 wk-old mice according to the expression of CD19 and CD5 and within the CD19 + CD5+ population according to the expression of CD21, B220, CD24, CD23 and CD38 markers. b, Column plots show the quantification of the percentage of CD19 + CD5+ B cells in liver and spleen bearing the markers shown in a. n = 4 mice per group. ** p < 0.01 ****p < 0.0001, ns, not significant (one-way ANOVA test).

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