Acute sleep deprivation induces a local brain transfer information increase in the frontal cortex in a widespread decrease context

Sleep deprivation (SD) has adverse effects on mental and physical health, affecting the cognitive abilities and emotional states. Specifically, cognitive functions and alertness are known to decrease after SD. The aim of this work was to identify the directional information transfer after SD on scal...

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Detalles Bibliográficos
Autores: Alonso López, Joan Francesc|||0000-0002-2980-6716, Romero Lafuente, Sergio|||0000-0002-8627-543X, Mañanas Villanueva, Miguel Ángel|||0000-0001-9836-6083, Alcalá Álvarez, Marta, Antonijoan, Rosa Maria, Giménez Badia, Sandra
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/91073
Acceso en línea:https://hdl.handle.net/2117/91073
https://dx.doi.org/10.3390/s16040540
Access Level:acceso abierto
Palabra clave:Medical electronics
prolonged wakefulness
sleep deprivation (SD)
electroencephalography (EEG) transfer entropy (TE)
DEFAULT-MODE NETWORK
FUNCTIONAL CONNECTIVITY
HUMAN EEG
PREFRONTAL CORTEX
DEPENDENT CHANGES
THETA ACTIVITY
RESTING STATE
WAKING EEG
ELECTROENCEPHALOGRAM
WAKEFULNESS
Son
Electrònica mèdica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
Descripción
Sumario:Sleep deprivation (SD) has adverse effects on mental and physical health, affecting the cognitive abilities and emotional states. Specifically, cognitive functions and alertness are known to decrease after SD. The aim of this work was to identify the directional information transfer after SD on scalp EEG signals using transfer entropy (TE). Using a robust methodology based on EEG recordings of 18 volunteers deprived from sleep for 36 h, TE and spectral analysis were performed to characterize EEG data acquired every 2 h. Correlation between connectivity measures and subjective somnolence was assessed. In general, TE showed medium-and long-range significant decreases originated at the occipital areas and directed towards different regions, which could be interpreted as the transfer of predictive information from parieto-occipital activity to the rest of the head. Simultaneously, short-range increases were obtained for the frontal areas, following a consistent and robust time course with significant maps after 20 h of sleep deprivation. Changes during sleep deprivation in brain network were measured effectively by TE, which showed increased local connectivity and diminished global integration. TE is an objective measure that could be used as a potential measure of sleep pressure and somnolence with the additional property of directed relationships.