Telomere length and pediatric obesity: A review

Obesity is a chronic disease, which needs to be early detected early and treated in order prevent its complications. Changes in telomere length (TL) have been associated with obesity and its complications, such as diabetes mellitus and metabolic syndrome. Therefore, we conducted a systematic review...

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Autor: Azcona-San-Julián, M.C. (María Cristina)|||/items/89d7bb2f-b633-4413-bc4d-cddf6026e848
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/115890
Acceso en línea:https://hdl.handle.net/10171/115890
Access Level:acceso abierto
Palabra clave:Obesity
Overweight
Telomere length
Children
Adolescents
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spelling Telomere length and pediatric obesity: A reviewAzcona-San-Julián, M.C. (María Cristina)|||/items/89d7bb2f-b633-4413-bc4d-cddf6026e848ObesityOverweightTelomere lengthChildrenAdolescentsObesity is a chronic disease, which needs to be early detected early and treated in order prevent its complications. Changes in telomere length (TL) have been associated with obesity and its complications, such as diabetes mellitus and metabolic syndrome. Therefore, we conducted a systematic review to summarize results of studies that have measured TL in children and adolescents with obesity. Fourteen studies aiming to assess TL in pediatric patients with either obesity or who were overweight were included in this review. In conclusion, obesity and adiposity parameters are negatively associated with TL. Shorter telomeres are observed in children with obesity compared with their lean counterparts. Factors involved in obesity etiology, such as diet and physical activity, may contribute to maintenance of TL integrity. In the long term, TL change could be used as a biomarker to predict response to obesity treatment.MDPIDadun. Depósito Académico Digital Universidad de Navarra20212021-01-0120212021-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/115890reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/1158902026-06-21T12:47:57Z
dc.title.none.fl_str_mv Telomere length and pediatric obesity: A review
title Telomere length and pediatric obesity: A review
spellingShingle Telomere length and pediatric obesity: A review
Azcona-San-Julián, M.C. (María Cristina)|||/items/89d7bb2f-b633-4413-bc4d-cddf6026e848
Obesity
Overweight
Telomere length
Children
Adolescents
title_short Telomere length and pediatric obesity: A review
title_full Telomere length and pediatric obesity: A review
title_fullStr Telomere length and pediatric obesity: A review
title_full_unstemmed Telomere length and pediatric obesity: A review
title_sort Telomere length and pediatric obesity: A review
dc.creator.none.fl_str_mv Azcona-San-Julián, M.C. (María Cristina)|||/items/89d7bb2f-b633-4413-bc4d-cddf6026e848
author Azcona-San-Julián, M.C. (María Cristina)|||/items/89d7bb2f-b633-4413-bc4d-cddf6026e848
author_facet Azcona-San-Julián, M.C. (María Cristina)|||/items/89d7bb2f-b633-4413-bc4d-cddf6026e848
author_role author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Obesity
Overweight
Telomere length
Children
Adolescents
topic Obesity
Overweight
Telomere length
Children
Adolescents
description Obesity is a chronic disease, which needs to be early detected early and treated in order prevent its complications. Changes in telomere length (TL) have been associated with obesity and its complications, such as diabetes mellitus and metabolic syndrome. Therefore, we conducted a systematic review to summarize results of studies that have measured TL in children and adolescents with obesity. Fourteen studies aiming to assess TL in pediatric patients with either obesity or who were overweight were included in this review. In conclusion, obesity and adiposity parameters are negatively associated with TL. Shorter telomeres are observed in children with obesity compared with their lean counterparts. Factors involved in obesity etiology, such as diet and physical activity, may contribute to maintenance of TL integrity. In the long term, TL change could be used as a biomarker to predict response to obesity treatment.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01
2021
2021-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/115890
url https://hdl.handle.net/10171/115890
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
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