Streptococcus agalactiae Serotype Distribution and Antimicrobial Susceptibility in Pregnant Women in Gabon, Central Africa

Neonatal invasive disease due to Streptococcus agalactiae is life threatening and preventive strategies suitable for resource limited settings are urgently needed. Protective coverage of vaccine candidates based on capsular epitopes will relate to local epidemiology of S. agalactiae serotypes and su...

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Detalhes bibliográficos
Autores: Belard, Sabine, Toepfner, Nicole, Capan-Melser, Mesküre, Mombo-Ngoma, Ghyslain, Zoleko-Manego, Rella, Groger, Mirjam, Matsiegui, Pierre-Blaise, Agnandji, Selidji Todagbe, Adegnika, Ayôla A., González, Raquel, Kremsner, Peter G., Menéndez, Clara, Ramharter, Michael, Berner, Reinhard
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/69249
Acesso em linha:https://hdl.handle.net/2445/69249
Access Level:acceso abierto
Palavra-chave:Estreptococs
Medicaments antibacterians
Embarassades
Gabon
Streptococcus
Antibacterial agents
Pregnant women
Descrição
Resumo:Neonatal invasive disease due to Streptococcus agalactiae is life threatening and preventive strategies suitable for resource limited settings are urgently needed. Protective coverage of vaccine candidates based on capsular epitopes will relate to local epidemiology of S. agalactiae serotypes and successful management of critical infections depends on timely therapy with effective antibiotics. This is the first report on serotype distribution and antimicrobial susceptibility of S. agalactiae in pregnant women from a Central African region. Serotypes V, III, and Ib accounted for 88/109 (81%) serotypes and all isolates were susceptible to penicillin and clindamycin while 13% showed intermediate susceptibility to erythromycin.