Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?

Background: Subthreshold depressive symptoms significantly hinder functional recovery in bipolar disorder (BD). While most studies use a global score to assess the impact of these symptoms on functioning, this study examines which specific subthreshold depressive symptoms mostly impede functional re...

Descripción completa

Detalles Bibliográficos
Autores: Bonnín Roig, Caterina del Mar, Montejo Egido, Laura, Torrent Font, Carla, Sánchez-Moreno, José, Diego-Adeliño, Javier de, Solé Cabezuelo, Brisa, Roca Tutusaus, Xavier, Hidalgo Mazzei, Diego, Borràs, Roger, Clougher, Derek, Valentí Ribas, Marc, Martínez-Arán, Anabel, 1971-, Cardoner, N. (Narcís), Vieta i Pascual, Eduard, 1963-
Tipo de recurso: artículo
Fecha de publicación:2026
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/228478
Acceso en línea:https://hdl.handle.net/2445/228478
Access Level:acceso abierto
Palabra clave:Depressió psíquica
Diagnòstic
Trastorn bipolar
Mental depression
Diagnosis
Manic-depressive illness
id ES_42e59581f3554c50df33a3e20587799e
oai_identifier_str oai:recercat.cat:2445/228478
network_acronym_str ES
network_name_str España
repository_id_str
spelling Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?Bonnín Roig, Caterina del MarMontejo Egido, LauraTorrent Font, CarlaSánchez-Moreno, JoséDiego-Adeliño, Javier deSolé Cabezuelo, BrisaRoca Tutusaus, XavierHidalgo Mazzei, DiegoBorràs, RogerClougher, DerekValentí Ribas, MarcMartínez-Arán, Anabel, 1971-Cardoner, N. (Narcís)Vieta i Pascual, Eduard, 1963-Depressió psíquicaDiagnòsticTrastorn bipolarMental depressionDiagnosisManic-depressive illnessBackground: Subthreshold depressive symptoms significantly hinder functional recovery in bipolar disorder (BD). While most studies use a global score to assess the impact of these symptoms on functioning, this study examines which specific subthreshold depressive symptoms mostly impede functional recovery in patients with BD in remission. Method: The sample comprised a total of 413 patients with BD. Subthreshold depressive symptoms were assessed using the 17-item Hamilton Depression Rating Scale (HAM-D), and psychosocial functioning was measured with the Functioning Assessment Short Test (FAST). Bivariate analyses were performed to identify items from the HAM-D as well as other clinical and demographic variables associated with functional impairment. Multivariate linear regression analyses were conducted including the variables that demonstrated significant associations in the bivariate analyses. Results: The linear regression model for the FAST total score demonstrated that "psychomotor retardation" (item 8) had the strongest association on psychosocial functioning (β = 6,9; p < 0,001), followed by "feelings of guilt" (item 2) (β = 5,75; p < 0,001) "work and activities" (item 7) (β = 5,38; p < 0,001) and "somatic anxiety" (item 11) (β = 3,45; p < 0,001). Other significant clinical variables included antipsychotic use, older age, fewer years of education and male sex. This model explained 39,6% of the variance in the FAST total score (R2 = 0,396; Adjusted R2 = 0,375; F(399,13) = 20,04; p < 0,001). Conclusions: Specific subthreshold symptoms, including psychomotor retardation, apathy, guilt and somatic anxiety significantly influence psychosocial functioning. These findings highlight the importance of specifically targeting these symptoms to achieve functional recovery, even when patients are clinically stable.Elsevier B.V.2026202620262026info:eu-repo/semantics/articleinfo:eu-repo/semantics/PublishedVersion10 p.application/pdfhttps://hdl.handle.net/2445/228478Articles publicats en revistes (Psicologia Clínica i Psicobiologia)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1016/j.jad.2026.121442Journal of Affective Disorders, 2026, vol. 403https://doi.org/10.1016/j.jad.2026.121442cc-by (c) Bonnín Roig, Caterina del Mar et al. , 2026http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/2284782026-05-29T05:05:01Z
dc.title.none.fl_str_mv Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
title Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
spellingShingle Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
Bonnín Roig, Caterina del Mar
Depressió psíquica
Diagnòstic
Trastorn bipolar
Mental depression
Diagnosis
Manic-depressive illness
title_short Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
title_full Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
title_fullStr Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
title_full_unstemmed Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
title_sort Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back?
dc.creator.none.fl_str_mv Bonnín Roig, Caterina del Mar
Montejo Egido, Laura
Torrent Font, Carla
Sánchez-Moreno, José
Diego-Adeliño, Javier de
Solé Cabezuelo, Brisa
Roca Tutusaus, Xavier
Hidalgo Mazzei, Diego
Borràs, Roger
Clougher, Derek
Valentí Ribas, Marc
Martínez-Arán, Anabel, 1971-
Cardoner, N. (Narcís)
Vieta i Pascual, Eduard, 1963-
author Bonnín Roig, Caterina del Mar
author_facet Bonnín Roig, Caterina del Mar
Montejo Egido, Laura
Torrent Font, Carla
Sánchez-Moreno, José
Diego-Adeliño, Javier de
Solé Cabezuelo, Brisa
Roca Tutusaus, Xavier
Hidalgo Mazzei, Diego
Borràs, Roger
Clougher, Derek
Valentí Ribas, Marc
Martínez-Arán, Anabel, 1971-
Cardoner, N. (Narcís)
Vieta i Pascual, Eduard, 1963-
author_role author
author2 Montejo Egido, Laura
Torrent Font, Carla
Sánchez-Moreno, José
Diego-Adeliño, Javier de
Solé Cabezuelo, Brisa
Roca Tutusaus, Xavier
Hidalgo Mazzei, Diego
Borràs, Roger
Clougher, Derek
Valentí Ribas, Marc
Martínez-Arán, Anabel, 1971-
Cardoner, N. (Narcís)
Vieta i Pascual, Eduard, 1963-
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Depressió psíquica
Diagnòstic
Trastorn bipolar
Mental depression
Diagnosis
Manic-depressive illness
topic Depressió psíquica
Diagnòstic
Trastorn bipolar
Mental depression
Diagnosis
Manic-depressive illness
description Background: Subthreshold depressive symptoms significantly hinder functional recovery in bipolar disorder (BD). While most studies use a global score to assess the impact of these symptoms on functioning, this study examines which specific subthreshold depressive symptoms mostly impede functional recovery in patients with BD in remission. Method: The sample comprised a total of 413 patients with BD. Subthreshold depressive symptoms were assessed using the 17-item Hamilton Depression Rating Scale (HAM-D), and psychosocial functioning was measured with the Functioning Assessment Short Test (FAST). Bivariate analyses were performed to identify items from the HAM-D as well as other clinical and demographic variables associated with functional impairment. Multivariate linear regression analyses were conducted including the variables that demonstrated significant associations in the bivariate analyses. Results: The linear regression model for the FAST total score demonstrated that "psychomotor retardation" (item 8) had the strongest association on psychosocial functioning (β = 6,9; p < 0,001), followed by "feelings of guilt" (item 2) (β = 5,75; p < 0,001) "work and activities" (item 7) (β = 5,38; p < 0,001) and "somatic anxiety" (item 11) (β = 3,45; p < 0,001). Other significant clinical variables included antipsychotic use, older age, fewer years of education and male sex. This model explained 39,6% of the variance in the FAST total score (R2 = 0,396; Adjusted R2 = 0,375; F(399,13) = 20,04; p < 0,001). Conclusions: Specific subthreshold symptoms, including psychomotor retardation, apathy, guilt and somatic anxiety significantly influence psychosocial functioning. These findings highlight the importance of specifically targeting these symptoms to achieve functional recovery, even when patients are clinically stable.
publishDate 2026
dc.date.none.fl_str_mv 2026
2026
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/PublishedVersion
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/228478
url https://hdl.handle.net/2445/228478
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1016/j.jad.2026.121442
Journal of Affective Disorders, 2026, vol. 403
https://doi.org/10.1016/j.jad.2026.121442
dc.rights.none.fl_str_mv cc-by (c) Bonnín Roig, Caterina del Mar et al. , 2026
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Bonnín Roig, Caterina del Mar et al. , 2026
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 10 p.
application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (Psicologia Clínica i Psicobiologia)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869406978664562689
score 15,812455

Similares en LA Referencia