Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study

Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-mat...

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Detalles Bibliográficos
Autores: Papantoniou, Kyriaki, Castaño-Vinyals, Gemma, Espinosa, Ana, Turner, Michelle C., Martín Sánchez, Vicente, Casabonne, Delphine, Aragonès Sanz, Núria, Gómez Acebo, Inés, Ardanaz, Eva, Jimenez Moleon, Jose Juan, Amiano, Pilar, Molina Barceló, Ana, Alguacil, Juan, Fernández Tardón, Guillermo, Huerta, José María, Hernández Segura, Natalia, Pérez Gómez, Beatriz, Llorca, Javier, Vidán Alli, Juana, Olmedo Requena, Rocío, Gil, Leire, Castañon López, Carmen, Pollan, Marina, Kogevinas, Manolis, Moreno Aguado, Víctor
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/179173
Acceso en línea:https://hdl.handle.net/2445/179173
Access Level:acceso abierto
Palabra clave:Càncer gastrointestinal
Factors de risc en les malalties
Son
Cáncer gastrointestinal
Colorectal cancer
Risk factors in diseases
Sleep
Gastrointestinal cancer
Descripción
Sumario:Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-matched population controls, recruited in the MCC-Spain case-control study (2008-2013). Sleep information, socio-demographic and lifestyle characteristics were obtained through personal interviews. Multivariable adjusted logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (CI) for cancer, across categories of sleep duration (≤ 5, 6, 7, 8, ≥ 9 hours/day), daytime napping frequency (naps/week) and duration (minutes/nap). Compared to 7 hours of sleep, long sleep was associated with increased odds of colorectal (OR≥9 hours: 1.59; 95%CI 1.30-1.94) and gastric cancer (OR≥9 hours: 1.95; 1.37-2.76); short sleep was associated with increased odds of gastric cancer (OR≤5 hours: 1.32; 0.93-1.88). Frequent and long daytime naps increased the odds of colorectal (OR6-7 naps/week, ≥30 min: 1.32; 1.14-1.54) and gastric cancer (OR6-7 naps/week, ≥30 min: 1.56; 1.21-2.02). Effects of short sleep and frequent long naps were stronger among participants with night shift-work history. Sleep and circadian disruption may jointly play a role in the etiology of colorectal and gastric cancer.

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