Detection of a 73-75 kDa and a 123 kDa fractions of Leishmania antigen in urine of patients with visceral leishmaniosis

Two polypeptide fractions of 72-75 kD were detected in the urine of 14 of 15 patients with visceral leishmaniasis (VL) and another fraction of 123 kD was found in 10 of the 15 patients by using a Western blot technique. None of these fractions was detected in the urine of 20 controls. These results...

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Detalles Bibliográficos
Autores: Colmenares Brunet, Maria de, Portús Vinyeta, Montserrat, Riera Lizandra, Ma. Cristina, Gállego Culleré, M. (Montserrat), Aisa Nache, Maria Jesús, Torras, S., Muñoz, C.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1995
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/123784
Acceso en línea:https://hdl.handle.net/2445/123784
Access Level:acceso abierto
Palabra clave:Leishmaniosi
Leishmània
Diagnòstic
Orina
Leishmaniasis
Leishmania
Diagnosis
Urine
Descripción
Sumario:Two polypeptide fractions of 72-75 kD were detected in the urine of 14 of 15 patients with visceral leishmaniasis (VL) and another fraction of 123 kD was found in 10 of the 15 patients by using a Western blot technique. None of these fractions was detected in the urine of 20 controls. These results suggest that antigen detection in urine could be a powerful, noninvasive method for VL diagnosis