Novel trans-disubstituted hexaaza-macrocyclic ligands containing pyridine head units: Synthesis, disubstitution and colorimetric properties

A trans-N,N′-methylated hexaazamacrocycle precursor L3, derived from the hexadentate polyamine macrocycle L (Py2[18]aneN6), was synthesized for the first time. The crystal structures of the intermediates L1·8H2O and L2I2·H2O showing two trans quaternary nitrogen atoms have also been determined by si...

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Detalhes bibliográficos
Autores: Lamelas, Rodrigo, García, Verónica, Liñares, Araceli, Bastida de la Calle, Rufina, Labisbal Viqueira, María Elena, Fernández Lodeiro, Adrián, Lodeiro, Carlos, Núñez González, Cristina
Formato: artículo
Fecha de publicación:2016
País:España
Recursos:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/46136
Acesso em linha:https://hdl.handle.net/10347/46136
Access Level:acceso abierto
Palavra-chave:Disubstitution
Hexaazamacrocycle
Colorimetric
Anion sensor
Urea/thiourea
Solid support
2303 Química inorgánica
Descrição
Resumo:A trans-N,N′-methylated hexaazamacrocycle precursor L3, derived from the hexadentate polyamine macrocycle L (Py2[18]aneN6), was synthesized for the first time. The crystal structures of the intermediates L1·8H2O and L2I2·H2O showing two trans quaternary nitrogen atoms have also been determined by single-crystal X-ray crystallography. By the alkylation of the trans secondary amines present in L3, two novel macrocyclic molecular probes 1 and 2 linked to two nitrophenylurea and two nitrophenylthiourea groups, respectively, are reported. Crystals of 1·2CDCl3 suitable for single-crystal X-ray diffraction analysis were also obtained. The coordination ability of compounds 1 and 2 toward hydrated nitrate salts of cobalt(II), nickel(II), copper(II), zinc(II) and cadmium(II) was studied. Their responses toward different anions (fluoride (F−), chloride (Cl−), bromide (Br−), iodide (I−), hydroxide (OH−), acetate (AcO−), cyanide (CN−), dihydrogen phosphate (H2PO4−), nitrate (NO3−) and perchlorate (ClO4−)) in DMSO solution were evaluated by UV–vis absorption spectroscopy. The immobilization of probe 1 in cellulose supported systems to evaluate its efficiency in the fast recognition of different anions (F−, AcO−, CN−, H2PO4−) in aqueous phase was also described