GSK-3ß orchestrates the inhibitory innervation of adult-born dentate granule cells in vivo

This study was supported by the following: The European Research Council (ERC) (ERC-CoG-2020-101001916 (MLLM)); the Spanish Ministry of Economy and Competitiveness (PID2020-113007RB-I00, SAF-2017-82185-R, and RYC-2015-171899 (MLLM)); The Alzheimer ́s Association (2015-NIRG-340709, AARG-17-528125, an...

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Detalles Bibliográficos
Autores: Moreno-Jiménez, E.P., Flor-García, Miguel, Hernández-Vivanco, Alicia, Terreros-Roncal, Julia, Rodríguez‐Moreno, Carla B., Toni, N., Méndez, Pablo, Llorens-Martín, María
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/345673
Acceso en línea:http://hdl.handle.net/10261/345673
Access Level:acceso abierto
Palabra clave:Adult hippocampal neurogenesis
Alzheimer´s disease
Behavior
Electrophysiology
GSK-3β
Gephyrin
Retrovirus.
Descripción
Sumario:This study was supported by the following: The European Research Council (ERC) (ERC-CoG-2020-101001916 (MLLM)); the Spanish Ministry of Economy and Competitiveness (PID2020-113007RB-I00, SAF-2017-82185-R, and RYC-2015-171899 (MLLM)); The Alzheimer ́s Association (2015-NIRG-340709, AARG-17-528125, and AARG-17-528125-RAPID (MLLM)); The Association for Frontotemporal Degeneration (2016 Basic Science Pilot Grant Award (MLLM)); the Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED, Spain (MLLM)), and the Swiss National Science Foundation (NT). Institutional grants from the Fundación Ramón Areces and Banco de Santander to the CBMSO are also acknowledged. The salary of EPMJ was supported by a 2018 Neuroscience Doctoral fellowship from the Fundación Tatiana Pérez de Guzmán and an EMBO Scientific Exchange Grant. The salary of MFG was supported by a “Formación de Personal Investigador” (FPI) contract, associated with the SAF-2017-82185-R grant (MLLM), supported by the Spanish Ministry of Economy and Competitiveness (PRE2018-085233). The salary of JTR was supported by a Doctoral fellowship from the Universidad Autónoma de Madrid (FPI-UAM 2017 program). The salary of CBRM is supported by “Subvenciones para la promoción de empleo joven e Implantación de la garantía juvenil en I+D+i 2018” (PEJ2018-001725-A) awarded by the Spanish Ministry of Economy and Competitiveness to MLLM. PM and AHV were supported by the Spanish Ministry of Economy and Competitiveness grant PID2020-112824GB-100 funded by MCIN/AEI/https://doi.org/10.13039/501100011033. The authors would like to thank Dr. Cafini for generating the Gephyrin:mCherry retrovirus.