Plasmonic biosensors

In-vitro diagnostics (IVD) has become an in-demand area with a high-achievement transformation due to the expansion of new technologies. Technology has grown from time-consuming laboratory techniques to modern automated immunoassays and progressed with real-time sensing through the emergence of bios...

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Detalles Bibliográficos
Autores: Giarola, Juliana Fatima|||0000-0002-2121-0328, Estévez, M. Carmen|||0000-0003-3694-7186, Lechuga, Laura M.|||0000-0001-5187-5358
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:302391
Acceso en línea:https://ddd.uab.cat/record/302391
https://dx.doi.org/urn:doi:10.1016/j.trac.2024.117763
Access Level:acceso abierto
Palabra clave:Surface plasmon resonance
Biosensor
Optical devices
Autoantibodies
Autoimmune disease
Diagnosis
Descripción
Sumario:In-vitro diagnostics (IVD) has become an in-demand area with a high-achievement transformation due to the expansion of new technologies. Technology has grown from time-consuming laboratory techniques to modern automated immunoassays and progressed with real-time sensing through the emergence of biosensor devices. Plasmonic biosensors are one of the most employed optical biosensors and stand out for their versatility and wide range of applications in diagnostic tests. One of the clinical diagnostics areas of growing interest is autoimmune diseases (AD), which have been increasingly prevalent worldwide. There is a rising demand for reliable and early AD diagnosis tools. This review highlights the main challenges for early AD diagnostics and the advanced plasmonic biosensors that have been exploited for AD biomarker detection, including brief descriptions of their analytical performance. Finally, the prospects and trends in this area are outlined, thinking about developing multiplexed platforms capable of addressing the multianalyte nature of one disease.