Changes in corneal biomechanical properties after 24 hours of continuous intraocular pressure monitoring using a contact lens sensor

Objective: This study was designed to assess changes in corneal topography and biomechanics after intraocular pressure (IOP) monitoring using the Triggerfish contact lens sensor (CLS). Methods: For this prospective study, 30 eyes of 30 subjects: 14 healthy subjects (G1) and 6 glaucoma patients (G2),...

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Detalles Bibliográficos
Autores: Morales Fernández, Laura, García Bella, Javier, Martínez De La Casa Fernández-Borrella, José María, Sánchez Jean, Rubén, Sáenz Francés, Federico, Arriola Villalobos, Pedro, Perucho González, Lucía, Santos Bueso, Enrique Miguel, García Feijoo, Julián
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/18330
Acceso en línea:https://hdl.handle.net/20.500.14352/18330
Access Level:acceso abierto
Palabra clave:617.7-089.243
617.7-007.681
617.713-073.75
Cornea
Intraocular pressure
Contact lens sensor
Corneal biomechanical properties
Glaucoma
Corneal topography
Pentacam
Oftalmología
Lentes de contacto
Técnicas de la imagen
3201.09 Oftalmología
3311.11 Instrumentos ópticos
Descripción
Sumario:Objective: This study was designed to assess changes in corneal topography and biomechanics after intraocular pressure (IOP) monitoring using the Triggerfish contact lens sensor (CLS). Methods: For this prospective study, 30 eyes of 30 subjects: 14 healthy subjects (G1) and 6 glaucoma patients (G2), were recruited for 24 hours of continuous IOP monitoring using the CLS. The following measurements were taken before CLS fitting and after lens removal: maximum keratometry (Kmax), mean keratometry (MK), and corneal astigmatism (Cyl) measured through Pentacam corneal topography, and the corneal biomechanical variables corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer (ORA). Results: Pentacam data revealed significant changes after CLS removal in Kmax (+3.14 ± 2.46 D, p = 0.002), MK (+0.52 ± 0.63 D, p = 0.02), and Cyl (+0.48 ± 0.53 D, p = 0.019) in G1; and Kmax (+1.38 ± 1.43 D, p = 0.002) in G2. The changes observed were more pronounced in G1 than in G2 but differences were not significant. The ORA results indicated higher CH (11.35 ± 2.42 vs 8.17 ± 2.09) and CRF (10.3 ± 2.03 vs 9.1 ± 1.81) before lens fitting in G1 than G2, while no significant changes were produced after CLS removal in either group. Conclusions: The use of CLS for IOP monitoring over 24 hours caused topographic changes in both healthy subjects and glaucoma patients. No changes were produced in corneal biomechanics.