Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease

In high-income countries, ischaemic heart disease is the leading cause of death in women and men, accounting for more than 20% of deaths in both sexes. However, women are less likely to receive guideline-recommended percutaneous coronary intervention (PCI) than men. Women undergoing PCI have poorer...

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Autores: Sambola-Ayala, Antonia, Del Blanco, Bruno García, Kunadian, Vijay, Vogel, Birgit, Chieffo, Alaide, Vidal, María, Ratcovich, Hanna, Botti, Giulia, Wilkinson, Chris, Mehran, Roxana
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:319573
Acceso en línea:https://ddd.uab.cat/record/319573
https://dx.doi.org/urn:doi:10.15420/ecr.2022.24
Access Level:acceso abierto
Palabra clave:Percutaneous coronary intervention
Women
Prognosis
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spelling Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart DiseaseSambola-Ayala, AntoniaDel Blanco, Bruno GarcíaKunadian, VijayVogel, BirgitChieffo, AlaideVidal, MaríaRatcovich, HannaBotti, GiuliaWilkinson, ChrisMehran, RoxanaPercutaneous coronary interventionWomenPrognosisIn high-income countries, ischaemic heart disease is the leading cause of death in women and men, accounting for more than 20% of deaths in both sexes. However, women are less likely to receive guideline-recommended percutaneous coronary intervention (PCI) than men. Women undergoing PCI have poorer unadjusted outcomes because they are older and have greater comorbidity than men, but uncertainty remains whether sex affects outcome after these differences in clinical characteristics are considered. In this paper, we review recent published evidence comparing outcomes between men and women undergoing PCI. We focus on the sex differences in PCI outcomes in different scenarios: acute coronary syndromes, stable angina and complex lesions, including the approach of left main coronary artery. We also review how gender is considered in recent guidelines and offer a common clinical scenario to illustrate the contemporary management strategies an interventional cardiologist should consider when performing PCI on a female patient. 22023-01-0120232023-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/319573https://dx.doi.org/urn:doi:10.15420/ecr.2022.24reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3195732026-06-06T12:50:31Z
dc.title.none.fl_str_mv Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
title Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
spellingShingle Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
Sambola-Ayala, Antonia
Percutaneous coronary intervention
Women
Prognosis
title_short Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
title_full Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
title_fullStr Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
title_full_unstemmed Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
title_sort Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease
dc.creator.none.fl_str_mv Sambola-Ayala, Antonia
Del Blanco, Bruno García
Kunadian, Vijay
Vogel, Birgit
Chieffo, Alaide
Vidal, María
Ratcovich, Hanna
Botti, Giulia
Wilkinson, Chris
Mehran, Roxana
author Sambola-Ayala, Antonia
author_facet Sambola-Ayala, Antonia
Del Blanco, Bruno García
Kunadian, Vijay
Vogel, Birgit
Chieffo, Alaide
Vidal, María
Ratcovich, Hanna
Botti, Giulia
Wilkinson, Chris
Mehran, Roxana
author_role author
author2 Del Blanco, Bruno García
Kunadian, Vijay
Vogel, Birgit
Chieffo, Alaide
Vidal, María
Ratcovich, Hanna
Botti, Giulia
Wilkinson, Chris
Mehran, Roxana
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Percutaneous coronary intervention
Women
Prognosis
topic Percutaneous coronary intervention
Women
Prognosis
description In high-income countries, ischaemic heart disease is the leading cause of death in women and men, accounting for more than 20% of deaths in both sexes. However, women are less likely to receive guideline-recommended percutaneous coronary intervention (PCI) than men. Women undergoing PCI have poorer unadjusted outcomes because they are older and have greater comorbidity than men, but uncertainty remains whether sex affects outcome after these differences in clinical characteristics are considered. In this paper, we review recent published evidence comparing outcomes between men and women undergoing PCI. We focus on the sex differences in PCI outcomes in different scenarios: acute coronary syndromes, stable angina and complex lesions, including the approach of left main coronary artery. We also review how gender is considered in recent guidelines and offer a common clinical scenario to illustrate the contemporary management strategies an interventional cardiologist should consider when performing PCI on a female patient.
publishDate 2023
dc.date.none.fl_str_mv 2
2023-01-01
2023
2023-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
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http://purl.org/coar/version/c_970fb48d4fbd8a85
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https://dx.doi.org/urn:doi:10.15420/ecr.2022.24
url https://ddd.uab.cat/record/319573
https://dx.doi.org/urn:doi:10.15420/ecr.2022.24
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
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https://creativecommons.org/licenses/by-nc/4.0/
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http://purl.org/coar/access_right/c_abf2
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dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
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