Atom Transfer Radical Reactions as a Tool for Olefin Functionalization : On the Way to Practical Applications

Transition-metal-catalyzed atom transfer radical reactions of halogenated compounds with olefins constitute a versatile tool in organic synthesis within the area of C–C bond forming transformations. The inter- or intramolecular versions, atom transfer radical addition (ATRA) or cyclization (ATRC), r...

Descripción completa

Detalles Bibliográficos
Autores: Muñoz Molina, José María, Rodríguez Belderraín, Tomás, Pérez Romero, Pedro José
Tipo de recurso: artículo
Fecha de publicación:2011
País:España
Institución:Universidad de Huelva (UHU)
Repositorio:Arias Montano. Repositorio Institucional de la Universidad de Huelva
Idioma:inglés
OAI Identifier:oai:ariasmontano.uhu.es:10272/11566
Acceso en línea:http://hdl.handle.net/10272/11566
Access Level:acceso abierto
Palabra clave:ATRA reactions
Homogeneous catalysis
Transition metals
Radicals
Olefins
Descripción
Sumario:Transition-metal-catalyzed atom transfer radical reactions of halogenated compounds with olefins constitute a versatile tool in organic synthesis within the area of C–C bond forming transformations. The inter- or intramolecular versions, atom transfer radical addition (ATRA) or cyclization (ATRC), respectively, lead to the atom-economic, useful synthesis of compounds that can be further functionalized. This contribution summarizes the recent developments in this area in terms of catalyst design as well as the applicability of this methodology in sequential, domino, or tandem reactions.